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Frontline Nivolumab/Ipilimumab Provides Superior PFS Benefit Over Chemo in MSI-H/dMMR mCRC

Nivolumab/ipilimumab reduced the risk of disease progression or death vs chemotherapy in previously untreated patients with metastatic colorectal cancer. ....

France General , San Francisco , United States , Van Cutsem , Thierry Andre , University Pierre Et Marie Curie , Oncology Department , Bristol Myers Squibb , University Pierre , Marie Curie , Medical Oncology Department , Antoine Hospital , Cancers Symposium , Myers Squibb , Nivolumab Ipilimumab , Previously Untreated Patients With Metastatic Colorectal Cancer , Checkmate 8hw Trial , St Antoine Hospital ,

Nivolumab Plus Ipilimumab Improves PFS in Newly Diagnosed Metastatic Colorectal Cancer

The combination of nivolumab and ipilimumab led to a statistically significant and clinically meaningful improvement in progression-free survival per blinded independent central review compared with investigator’s choice of chemotherapy as frontline therapy in patients with metastatic colorectal cancer. ....

Dana Walker , Bristol Myers Squibb , Nivolumab And Ipilimumab , Patients With Metastatic Colorectal Cancer , Checkmate 8hw Trial ,