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Cureus | SARS-CoV-2 Mutations Responsible for Immune Evasion Leading to Breakthrough Infection

Background and objectives: India had faced a devastating second outbreak of COVID-19 infection, in which a majority of the viral sequences were found to be of the B.1.617.2 lineage (Delta-variant). While India and the world focused on vaccination, reports of vaccine-immunity evasion by the virus, termed “breakthrough cases”, emerged worldwide. Our study was focused on the primary objective to identify the mutations associated with breakthrough infections SARS-CoV-2.

Methods: In our study, we extracted the SARS-CoV-2 RNA (ribonucleic acid) from reverse transcription-polymerase chain reaction (RT-PCR) positive COVID-19 patients, and 150 random samples were sent for sequencing to the Centre for Cellular & Molecular Biology, Hyderabad. Whole genome sequences of 150 SARS-CoV-2 viral samples were analyzed thoroughly. We mostly found B.1.617 and its sub-lineages in the genomic sequencing results.

Results and interpretation: On further analysis of patient data, ....

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Ocho leones se contagiaron de covid-19 en India: Investigan si fueron infectados por humanos

Ocho leones se contagiaron de covid-19 en India: Investigan si fueron infectados por humanos
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Ocho leones dan positivo para covid-19 en un zoo de la India

Ocho leones dan positivo para covid-19 en un zoo de la India
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En la India, la Covid-19 ataca a ocho leones

En la India, la Covid-19 ataca a ocho leones
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Coronavirus en animales salvajes de la India: Ocho leones dan positivo

Coronavirus en animales salvajes de la India: Ocho leones dan positivo
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