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Celcuity Inc.: Celcuity Presents Data at AACR Annual Meeting Assessing Gedatolisib, a pan-PI3K/mTOR Inhibitor, in HER2-negative Breast and Ovarian Cancer Patient Tumors with Hyperactive RAS Network Signaling

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- Inhibition of hyperactive RAS network signaling is nine times more effective with gedatolisib than with a PI3K-α inhibitor -
- Synergistic cooperation between PI3K/mTOR and BCL signaling detected, suggesting potential patient benefit of combining gedatolisib with a BCL inhibitor -
MINNEAPOLIS, MN / ACCESSWIRE / April 12, 2021 / Celcuity Inc. (NASDAQ:CELC), a clinical-stage biotechnology company pursuing an integrated companion diagnostic (CDx) and therapeutic strategy for treating patients with cancer, presented results of studies evaluating gedatolisib (a pan-PI3K/mTOR inhibitor), inavolisib (a PI3K-
α inhibitor), and navitoclax (a BCL inhibitor) in breast and ovarian patient tumors. Results were presented in two e-posters at the American Association for Cancer Research (AACR) Annual Meeting. ....

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Celcuity Presents Data at AACR Annual Meeting Assessing Gedatolisib, a pan-PI3K/mTOR Inhibitor, in HER2-negative Breast and Ovarian Cancer Patient Tumors with Hyperactive RAS Network Signaling

Celcuity Presents Data at AACR Annual Meeting Assessing Gedatolisib, a pan-PI3K/mTOR Inhibitor, in HER2-negative Breast and Ovarian Cancer Patient Tumors with Hyperactive RAS Network Signaling
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Celcuity Reports Preliminary Data from Phase 1b Trial of Gedatolisib plus Ibrance® and Endocrine The

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08-Apr-2021
Celcuity Reports Preliminary Data from Phase 1b Trial of Gedatolisib plus Ibrance® and Endocrine Therapy for Patients with ER+/HER2- Metastatic Breast Cancer and Provides Corporate Update
Preliminary Phase 1b Data
- Gedatolisib showed a potentially differentiated safety and tolerability profile -
Corporate Update
- Proceeds from first $15 million tranche increase cash-on-hand to $44 million -
- Drug development capabilities and team broadened and expanded -
- Conference call and webcast scheduled for today, April 8 at 5 p.m. Eastern Time -
MINNEAPOLIS (BUSINESS WIRE) Celcuity Inc. (Nasdaq:CELC), a clinical-stage biotechnology company pursuing an integrated companion diagnostic and therapeutic strategy for treating patients with cancer, today reported preliminary data for the 103 patients enrolled in the expansion portion of an ongoing Phase 1b clinical trial evaluating ged ....

Sheri Smith , Bernhard Lampert , Celsignia Cdx , Arthur Decillis , Bristol Myers Squibb , Vicky Hahne , Marie Degayner Kuker , Robert Uhl , Johnr Macdonald , Brian Sullivan , Regulatory Affairs Professionals Society , Exchange Commission On , Eisai Co , Vp Clinical Research For Exelixis , University Of Georgia , Celcuity Inc , Armentum Partners , Sesen Bio Inc , Wm Pharmaceuticals , Innovatus Capital Partners , Preliminary Phase , Response Evaluation Criteria , Solid Tumors , Chief Medical , Chief Medical Officer , Senior Vice President ,

Celcuity Announces Worldwide Licensing Agreement with Pfizer to Develop and Commercialize Gedatolisi

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08-Apr-2021
Celcuity Announces Worldwide Licensing Agreement with Pfizer to Develop and Commercialize Gedatolisib, a First-in-Class PI3K/mTOR Inhibitor for Breast Cancer
-Preliminary data from 103 patients in the expansion portion of a Phase 1b clinical trial demonstrated the drug was well tolerated and anti-tumor activity was noted
- Unique opportunity to leverage CELsignia platform to advance development of a first-in-class targeted therapy
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Management to host conference call/webcast today, April 8, 2021, at 5:00 p.m. ET
MINNEAPOLIS (BUSINESS WIRE) #cancer Celcuity Inc. (Nasdaq:CELC), a clinical-stage biotechnology company pursuing an integrated companion diagnostic and therapeutic strategy for treating patients with cancer, today announced it has entered into a global licensing agreement with Pfizer Inc. (NYSE:PFE) granting Celcuity exclusive rights to Pfizer’s gedatolisib, a Phase 1b pan ....

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Celcuity Reports Preliminary Data from Phase 1b Trial of Gedatolisib plus Ibrance® and Endocrine Therapy for Patients with ER+/HER2- Metastatic Breast Cancer and Provides Corporate Update

Celcuity Reports Preliminary Data from Phase 1b Trial of Gedatolisib plus Ibrance® and Endocrine Therapy for Patients with ER+/HER2- Metastatic Breast Cancer and Provides Corporate Update
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Sheri Smith , Bernhard Lampert , Celsignia Cdx , Arthur Decillis , Bristol Myers Squibb , Vicky Hahne , Marie Degayner Kuker , Robert Uhl , Johnr Macdonald , Brian Sullivan , Regulatory Affairs Professionals Society , Exchange Commission On , Eisai Co , Vp Clinical Research For Exelixis , University Of Georgia , Celcuity Inc , Armentum Partners , Sesen Bio Inc , Wm Pharmaceuticals , Innovatus Capital Partners , Wall Street , Response Evaluation Criteria , Solid Tumors , Chief Medical , Chief Medical Officer , Senior Vice President ,