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Study discovers hidden mechanism behind rapid COVID variants

The SARS-CoV-2 virus that causes COVID has the unsettling ability of often generating variants of itself. Other viruses also mutate, but as SARS-CoV-2 quickly spread throughout the entire human population during the pandemic, killing millions, the virus' dynamic evolution posed a serious problem: it repeatedly challenged our bodies' immune response fighting the virus and hindered the process of getting updated vaccines ready. ....

Baylor College Of Medicine , United States , Catherinec Bradley , Alicex Wen , Matthewb Cooke , Shannone Ronca , Pamelan Luna , Christophe Herman , Pedroa Piedra , Scottr Kennedy , Alasdair Je Gordon , Brendanf Kohrn , Olivier Lichtarge , Vasanthi Avadhanula , Chen Wang , National Science Foundation , University Of Washington , Danl Duncan Comprehensive Cancer Center , National Institutes Of Health , Nature Microbiology , Baylor College , Study Corresponding Author , Human Genetics , Danl Duncan Comprehensive Cancer , Targeted Accurate , Texas Children ,

New technology uncovers mechanism affecting g

<p>Researchers at Baylor College of Medicine and collaborating institutions developed a new technology called tARC-seq that revealed a genetic mechanism affecting SARS-CoV-2 divergence and enabled the team to calculate SARS-CoV-2&rsquo;s mutation rate. Using tARC-seq, the researchers also captured new mutations in SARS-CoV-2 in infected cells in the lab that recapitulated observations revealed by worldwide pandemic viral sequencing data. The findings can be useful for monitoring viral evolution in the human population.</p>
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Baylor College Of Medicine , United States , Pedroa Piedra , Catherinec Bradley , Vasanthi Avadhanula , Alasdair Je Gordon , Brendanf Kohrn , Alicex Wen , Chen Wang , Pamelan Luna , Olivier Lichtarge , Matthewb Cooke , Shannone Ronca , Scottr Kennedy , Christophe Herman , University Of Washington , National Institutes Of Health , Danl Duncan Comprehensive Cancer Center , National Science Foundation , Method Of Research , Nature Microbiology , Baylor College , Danl Duncan Comprehensive Cancer , Targeted Accurate , Texas Children , National Institutes ,