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First eye drop for diabetic macular oedema on horizon after successful trial

Exonate, an mRNA therapy company focused on treatments for diabetic complications, has announced that its lead ophthalmology asset, EXN407, has achieved its prespecified endpoints in an early study. ....

Janssen Pharmaceuticals , Catherine Beech , Clinical Development , Eye Disease ,

First eye drop for diabetic macular oedema on horizon after successful trial

Exonate, an mRNA therapy company focused on treatments for diabetic complications, has announced that its lead ophthalmology asset, EXN407, has achieved its prespecified endpoints in an early study. ....

Janssen Pharmaceuticals , Catherine Beech , Clinical Development , Eye Disease ,

Handball-Pokal der Frauen: SG BBM Bietigheim jubelt nach hartem Kampf

Handball-Pokal der Frauen: SG BBM Bietigheim jubelt nach hartem Kampf
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Fazit: Hauptsache gewonnen : 18.02.2021, 07.25 Uhr

Fazit: Hauptsache gewonnen : 18.02.2021, 07.25 Uhr
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Exonate launches diabetic macular oedema trial

Exonate launches diabetic macular oedema trial
4th February 2021
Cambridge, UK-based Exonate has dose the first patient with its lead compound – EXN 407 – in a Phase Ib/II clinical trial investigating the drug in volunteers with centre-involved diabetic macular oedema (CI-DMO).
The clinical trial, launched as part of Exonate’s collaboration with Janssen Pharmacueticals, consists of a dose escalation phase during which three doses of EXN 407 and a placebo will be tested.
This will then be followed by an expansion phase with a larger cohort of patient volunteers and a longer drug dosing period.
The study will aim to demonstrate the safety and efficacy, as well as an exploratory end point of efficacy, through reduction in retinal thickness in a proportion of patients. ....

United Kingdom , Janssen Pharmacueticals , United Kingdom Based Exonate , Catherine Beech , ஒன்றுபட்டது கிஂக்டம் , கேத்தரின் பீச் ,