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Compliance-ready intact mass analysis of modified oligonucleotides and impurities using the BioAccord LC-MS System on SelectScience

Watch the latest scientific webinars on SelectScience. ....

Catalin Doneanu , Clinical Diagnostics , Drug Discovery , Life Sciences , மருத்துவ பரிசோதனை , மருந்து கண்டுபிடிப்பு , வாழ்க்கை அறிவியல் ,

Compliance-ready intact mass analysis of modified oligonucleotides and impurities using the BioAccord LC-MS System

Expert Insight: Compliance-ready intact mass analysis of modified oligonucleotides and impurities using the BioAccord LC-MS System
Watch this on-demand webinar to learn how the BioAccord LC-MS system delivers robust UPLC separations performance for a range of modified oligos
06 Jan 2021
Dr. Catalin Doneanu, Principal Chemist at Waters
As the pipeline for oligonucleotide-based therapeutics continues to grow, with over 300 currently in clinical trials, along with an increased demand for GMP/GLP-validated oligonucleotide reagents (including primers, probes, gRNA) for clinical DNA testing and sequencing, the need for robust, compliance-ready LC-MS analysis of oligonucleotides has never been greater.
Waters has designed the BioAccord LC-MS System to deliver robust, reproducible separations and accurate mass performance in a compact, easy-to-use format, one that facilitates deployment across regulated development, manufacturing and QC labs and supports a range of rou ....

Catalin Doneanu , Expert Insight , Principal Chemist , Alexa Fluor , நிபுணர் நுண்ணறிவு , ப்ரிந்ஸிபல் வேதியியலாளர் , அலெக்சா ஃவுளூர் ,