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EUSA Pharma: SYLVANT (siltuximab) Recommended by the National Comprehensive Cancer Network (NCCN) as the Preferred Treatment Option for Patients with Idiopathic Multicentric Castleman Disease (iMCD) regardless of histopathologic subtype


(1)
EUSA Pharma (UK) Limited (
EUSA Pharma ), a global biopharmaceutical company focused on oncology and rare diseases, announced that the National Comprehensive Cancer Network
(NCCN
) for B-Cell Lymphomas to include siltuximab (SYLVANT
) as the preferred primary treatment for patients with human immunodeficiency virus-negative [HIV(-)] and human herpesvirus 8-negative [HHV-8(-)] multicentric Castleman disease (MCD), also known as idiopathic multicentric Castleman disease (iMCD), regardless of histopathologic subtype.
1 Siltuximab is currently approved in more than 40 countries worldwide for the treatment of all histopathologic subtypes of iMCD, a rare, life-threatening and debilitating orphan condition of the lymph nodes and related tissues.
2,3 The update is based on a 2020 publication which demonstrated that there is insufficient evidence to guide treatment based solely on lymph node histopathologic subtype. ....

Hemel Hempstead , United Kingdom , United States , Kostenloser Wertpapierhandel , Lee Morley , David Fajgenbaum , Rebecca Kerr , National Comprehensive Cancer Network Inc , European Commission , Drug Administration , Castleman Disease Collaborative Network , Eusa Pharma United Kingdom Limited , University Of Pennsylvania , Pharma United Kingdom Ltd , National Comprehensive Cancer Network , National Comprehensive Cancer , Clinical Practice Guidelines , B Cell Lymphomas , Chief Executive Officer , Assistant Professor , Translational Medicine Human Genetics , Co Founder Executive Director , Castleman Disease Collaborative , Usage See , Product Characteristics , Practice Guidelines ,