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Tails on engineered T cells could help fight cancer

In a promising form of immunotherapy known as CAR T-cell (chimeric antigen receptor) therapy, the patient's T cells are engineered to better recognize and attack antigens on the surface of cancer cells. ....

Xiaoyu Zhou , Sidi Chen , Hanbing Cao , Lily Ramsey , Yale Center , Yale Cancer Center , Yale Stem Cell Center , Systems Biology Institute , Yale School Of Medicine , National Institutes Of Health , Us Department Of Defense , Yale School , Biomedical Data Science , Cancer Systems Biology , National Institutes , Cart Cell , Chimeric Antigen Receptor , Ctla 4 , T Cell ,

CAR T Therapy For Aggressive Childhood T Cell Leukemia

CAR T therapy has yet to be translated for T cell derived leukemias. One study leaves room for hope, as their CAR T product demonstrates early proof-of-concept. ....

University College Of London , National Health Services , New England Journal , Antigen Receptort Cell , Therapy Challenges , University College , National Health Services Trust , Cart Cell , Cart Therapy , T Cell Leukemia , T Cell Acute Lymphoblastic Leukemia , Cell Therapy , Gene Editing , Crispr Cas9 , Cart Cell Fratricide ,

Dr Matous on Barriers to CAR T-Cell Therapy Administration in Multiple Myeloma

Jeffrey V. Matous, MD, discusses potential strategies to overcome barriers to receiving CAR T-cell therapy for patients with multiple myeloma, and how the potential use of these agents in earlier lines could improve infusion wait times and rates of disease progression. ....

United States , Jeffreyv Matous , University Of Colorado Health Sciences Center , Colorado Blood Cancer Institute , Colorado Health Sciences Center , Multiple Myeloma , Cellular Therapy , Cilta Cel , Cartitude 1 Trial , Fda Approval , Cart Cell ,

Fred Hutch experts highlight research on cancer treatment advances, survivorship and precision oncology at ASCO

At the 2023 American Society for Clinical Oncology Annual Meeting to be held June 2-6 in Chicago, Illinois Fred Hutchinson Cancer Center experts will present research spanning survivorship, advances in treatments and clinical trials, how access to cancer care affects outcomes, integrative medicine and more. ....

United States , Sarah Psutka , Megan Othus , Ruben Raychaudhuri , Emily Liang , Fred Hutch , Andrew Coveler , Lauren Shih , Lily Ramsey , Noam Kopmar , Bart Scott , Natasha Kwendakwema , Shiba Khan , Scott Ramsey , Eric Chow , Manoj Menon , Shailender Bhatia , Joseph Unger , Qin Sun , Cristina Rodriguez , American Society Of Clinical Oncology , Fred Hutchinson Cancer Center , Cancer Research Network , Uganda Cancer Institute , Friends Of Cancer Research , American Society For Clinical Oncology Annual Meeting ,

New Zealand-China science relationship affirmed

Research, Science and Innovation Minister Dr Ayesha Verrall and the Chinese Minister of Science and Technology Wang Zhigang met in Wellington today and affirmed the two countries' long-standing science relationship. Minister Wang was in New Zealand for the 6th New Zealand-China Joint Commission Meeting on Science and Technology Cooperation. Following their meeting the ministers toured the Malaghan Institute of Medical Research at Victoria University Wellington. The Malaghan Institute has a joint venture with China's Hunan Zhaotai Medical Group to develop a new approach to fighting cancer called Car T-cell therapy. "China is one of our key science and innovation partners and Minister Wang and I confirmed our commitment to this strong relationship," Ayesha Verrall said. "We have significant mutual research interests, particularly in food, environmental and health sciences. New Zealand and Chinese scientists have been cooperating for more than 40 years and each year ....

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