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CAR T-Cell Therapy - Novel Form of Immunotherapy

CAR T-cell therapy is a type of gene therapy where the patient’s T-lymphocytes are genetically altered to target cancer cells within the patient’s body. ....

United States , Fred Hutchinson Institute , Drug Administration , Chimeric Antigen Receptort Cell , Cart Cell Therapy , Chimeric Antigen Receptor Cart Cell Therapy , Cellular Immunotherapy , T Cells ,

Recent Data on Axi-Cel in Lymphoma

Dr Leslie discusses two abstracts on axi-cel recently presented at ASH 2023: a subgroup analysis of ZUMA-7 and the 4-year follow-up from ZUMA-5. ....

Lori Leslie , Jamesk Mccloskey , Gloria Leslie , Peer Exchange , Research Programs , John Theurer Cancer Center , Hackensack University Medical Center , Hackensack University Medical , Associate Professor , Indolent Lymphoma , Mash 2023 , Zuma 7 , Axi Cel , Largeb Cell Lymphoma , Older Population , Cart Cell Therapy , Car T , Overall Survival , Indolent Lymphomas , Follicular Lymphoma , Marginal Zone Lymphoma , Relapsed Refractory Follicular Lymphoma ,

Dual-Targeted CAR T-Cell Therapy Displays Early Efficacy in Recurrent Glioblastoma

A CAR T-cell therapy directed toward 2 brain tumor–associated proteins displayed preliminary activity in recurrent glioblastoma. ....

United States , John Templeton Jr , Donaldm Orourke , Stephen Bagley , Human Brain Tumor Tissue Bank , Glioblastoma Translational Center , Response Assessment , Penn Medicine , John Templeton , Recurrent Glioblastoma , Cart Cell Therapy , Penn Medicine ,

Back to the Bench: Exploring the Potential of CAR T-Cell Therapy in Oncology

Miguel-Angel Perales, MD, and Caron A. Jacobson, MD, share insights regarding the context and implications of the recent actions by the FDA to add boxed warnings to CAR T-cell therapies. ....

Carona Jacobson , Miguel Angel Perales , Real World Impact , Cell Therapy , Largeb Cell Lymphoma , Angel Perales , Cart Cell , Cart Cell Therapy , Cart Cell Therapy Real World Data ,

The Future of CAR T-Cell Therapy in LBCL

Caron A. Jacobson, MD, and Miguel-Angel Perales, MD, look at both the regulatory and clinical components that will shape future research and utilization of CAR T-cell therapy in oncology and beyond. ....

Carona Jacobson , Miguel Angel Perales , Real World Impact , Cell Therapy , Largeb Cell Lymphoma , Cart Cell , Cart Cell Therapy , Cart Cell Therapy Real World Data ,