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Potential treatment of breast cancer through targeted drugs, reveals new study

Washington [US], May 2 (ANI): A team of researchers has discovered strong evidence that prolactin, a hormone responsible for breast growth and production of milk during pregnancy acts as a major contributor to breast cancer development and that the hormone could inform the creation of targeted drugs to treat multiple forms of the disease. ....

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Breakthrough study uncovers potential treatment of breast cancer through targeted drugs

Breakthrough study uncovers potential treatment of breast cancer through targeted drugs
Breakthrough study uncovers potential treatment of breast cancer through targeted drugs
Last Updated: Tue, Apr 27th, 2021, 10:20:08hrs
Washington [US], April 27 (ANI): A recent study led by researchers at the Virginia Commonwealth University (VCU) Massey Cancer Center found strong evidence that prolactin, a hormone responsible for breast growth and production of milk during pregnancy acts as a major contributor to breast cancer development and that the hormone could inform the creation of targeted drugs to treat multiple forms of the disease.
Hormones have proteins on their cell surface called receptors that receive and send biological messages and regulate cell function. Through research published in the journal npj (Nature Partner Journals) Breast Cancer, VCU Massey Cancer Center researcher Charles Clevenger, M.D., PhD, and his lab discovered a new, altered form of the prolact ....

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Prolactin hormone acts as a major contributor to breast cancer development, studies find

Prolactin hormone acts as a major contributor to breast cancer development, studies find
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Studies connect hormone to breast cancer and uncover potential for novel targeted drugs

Credit: VCU Massey Cancer Center
The hormone prolactin has long been understood to play a vital role in breast growth and development and the production of milk during pregnancy. But a pair of recent studies conducted at VCU Massey Cancer Center finds strong evidence that prolactin also acts as a major contributor to breast cancer development and that the hormone could inform the creation of targeted drugs to treat multiple forms of the disease.
Hormones have proteins on their cell surface called receptors that receive and send biological messages and regulate cell function. Through research published in
npj Breast Cancer, VCU Massey Cancer Center researcher Charles Clevenger, M.D., Ph.D., and his lab discovered a new, altered form of the prolactin receptor called the human prolactin receptor intermediate isoform (hPRLrI) that directly drives breast cancer. The researchers observed that this modified version of the prolactin receptor interacted with other forms of the ....

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