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Dark energy survey releases most precise look at the universe's evolution

In 29 new scientific papers, the Dark Energy Survey examines the largest-ever maps of galaxy distribution and shapes, extending more than 7 billion light-years across the Universe. The extraordinarily precise analysis, which includes data from the survey s first three years, contributes to the most powerful test of the current best model of the Universe, the standard cosmological model. However, hints remain from earlier DES data and other experiments that matter in the Universe today is a few percent less clumpy than predicted. ....

United States , University Of Chicago , United Kingdom , Kitt Peak National Observatory , South Korea , University Of Illinois , Cerro Pach , Verac Rubin , Iolkam Duag Kitt , Chris Davis , Alistair Walker , Steve Heathcote , Amanda Kocz , Cerro Tololo , Fermi Research Alliance , Funding Authority For , Technology Facilities Council Of The United Kingdom , Higher Education Funding Council For England , Technological Development , Office Of Science , National Accelerator Laboratory , Department Of Energy , Kavli Institute Of Cosmological Physics , Research In Astronomy , Us Department Of Energy Office Science , Dark Energy Survey ,

Phase transition inside the nucleus provides oncogenic function to mutant p53 in cancer


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IMAGE: Pathway of mutant p53 from liquid droplets to gel-like and solid-like (amyloid) states, in vitro and in cell.
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Credit: Guilherme de Oliveira
Cancer has been recently shown to be affected by protein clusters, particularly by the aggregation of mutant variants of the tumor suppressor protein p53, which are present in more than half of malignant tumors. However, how the aggregates are formed is not yet fully understood. The understanding of this process is expected to provide new therapeutic tools able to prevent proteins to clump and cancer progression.
In Brazil, researchers at the Federal University of Rio de Janeiro have identified a key mechanism behind the mutant p53 aggregation process, linked to cancer pathology, opening new paths for the development of novels drugs against the disease. ....

Rio De Janeiro , Estado Do Rio , Fernandop Almeida , Adrianil Felix , Yullim Passos , Yraima Cordeiro , Mayraa Marques , Michellef Mota , Giuliads Ferretti , Benjamin Jakobus , Tuane Vieira , Murilom Pedrote , Elainec Petronilho , Technology For Structural Biology , Technological Development Cnpq , Royal Society Of Chemistry , National Institute Of Science , University Of Rio De Janeiro , National Council For Scientifc , Carlos Chagas Filho Foundation For Research , Federal University , Chemical Science , Royal Society , Jerson Lima Silva , Lima Silva , Santos De Sousa ,

31% of dogs and 40% of cats tested positive to COVID-19 after owners' diagnoses


Article Title: Investigation of SARS-CoV-2 infection in dogs and cats of humans diagnosed with COVID-19 in Rio de Janeiro, Brazil
Funding: MMS: This study was supported by CGLab/MoH (General Laboratories Coordination of Brazilian Ministry of Health), CVSLR/FIOCRUZ (Coordination of Health Surveillance and Reference Laboratories of Oswaldo Cruz Foundation), The National Council for Scientific and Technological Development (CNPq) COVID-19 MCTI 402457/2020-0, INOVA VPPCB-005-FIO-20-2-69, and Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ) E26/210.196/2020.
Competing Interests: The authors have declared that no competing interests exist. ....

Rio De Janeiro , Estado Do Rio , Oswaldo Cruz , Rio Grande Do Sul , Cglab Mo , Reference Laboratories Of Oswaldo Cruz Foundation , Technological Development Cnpq , Laboratories Coordination Of Brazilian Ministry Health , National Council For Scientific , Coordination Of Health Surveillance , General Laboratories Coordination , Brazilian Ministry , Health Surveillance , Reference Laboratories , Oswaldo Cruz Foundation , National Council , Technological Development , Carlos Chagas Filho Foundation , Research Support , Medicine Health , ரியோ டி ஜானிரோ , எஸ்டாடோ செய் ரியோ , ஒஸ்வள்தோ குரூஸ் , ரியோ கிராண்டே செய் சூழ் , தொழில்நுட்ப வளர்ச்சி சந்பக் , தேசிய சபை க்கு அறிவியல் ,