Background and Objectives: Sub-Saharan Africa is home to 3.7 million older adults living with HIV, who experience high rates of comorbid conditions. Formal services other than HIV clinical care are largely unavailable. Overall, women are the mainstay of informal social support networks, and older women with HIV may face burdens due to family caregiving expectations. Thus, it is important to understand the extent of informal support provided to older adults living with HIV, and how this is affected by gender. Research Design and Methods: We examined differences in social networks, needs, social support and caregiving, and perceptions of support adequacy among women and men aged 50 and older living with HIV in Uganda (n = 101) and South Africa (n = 108), mostly rural and suburban populations, respectively. We used multiple regression to determine whether there was an association between gender and the amount of social support received and whether that varied by research site. Results: Me