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Novel PCSK9 Inhibitor Reduced LDL by 50%

Lerodalcibep, a third-generation PCSK9 inhibitor, reduced LDL by more than 50% vs placebo in patients with or at a high risk for CVD in the phase 3 LIBerate-HR trial.

South africaUnited statesEric klugAmerican college of cardiologyDivision of cardiologyUniversity of the witwatersrandEuropean society of cardiologyPrevention of cardiovascular disease councilVirginia commonwealth university school of pharmacyAmerican heart associationDrug administrationAmerican collegeScientific sessionEuropean societyVirginia commonwealth university schoolCardiovascular disease council

Factors to Consider When Deprescribing Hypertension Drugs

Experts offered tips on when to deprescribe hypertension medications against a backdrop of new research that is missing from current recommendations.

South koreaSoult ukpyolsiUnited statesNew orleansEugene yangReinhold kreutzKeithc ferdinandGerelds berensonEuropean society of hypertensionResearch provides insightPrevention of cardiovascular disease councilAmerican heart associationAmerican college of cardiologyInternational society of hypertensionTulane school of medicineCardiovascular disease council

Similar Outcomes With Enteric-Coated and Uncoated Aspirin: ADAPTABLE

The coating didn’t appear to diminish GI bleeding but, in better news, also didn’t dampen aspirin’s antiplatelet effects.

Amber sleemMark effronDave dixonDo ochsner medical centerNational patientClinical research networkPharmd virginia commonwealth universityVascular instituteOchsner medical centerNew orleansJohn ochsner heartNational patient centered clinical researchVirginia commonwealth universityAmerican collegeCardiovascular disease council

Cardiac Arrest Symptoms Differ Between Women and Men

Men are more likely to have chest pain before cardiac arrest, while women more often have shortness of breath, study finds.

United statesUniversity of illinoisSouth burlingtonPavitra kotini shahLos angelesSumeet chughSarah permanSherrie khadnangaAmbarish pandeySchmidt heart institute at cedarsUt southwestern medical centerFoundation advisory councilLancet digital healthUniversity of colorado school medicineAmerican heart associationAmerican heart

Migraine With Aura Doesn t Hone CV Risk Prediction in Middle-aged Women

In an observational analysis, these headaches were tied to double the CVD event risk but mattered little at the population level.

United statesDavel dixonAngelaa stantonPharmd virginia commonwealth universityAmerican heart association college of cardiologyJournal of the american college cardiologyWomen health studyPhd stanton migraine protocol incPrevention of cardiovascular disease councilAmerican collegeReynolds risk scoreAmerican heartVirginia commonwealth universityCardiovascular disease councilHealth studyStanton migraine protocol inc

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