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Pneumagen Announces Successful Clinical Proof of Concept for its Broad-Spectrum Antiviral Neumifil in Phase 2 Influenza Human Challenge Study

Pneumagen Announces Successful Clinical Proof of Concept for its Broad-Spectrum Antiviral Neumifil in Phase 2 Influenza Human Challenge Study
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Pneumagen Announces Neumifil™ is Efficacious In an Established Model of COVID-19 Infection


Pneumagen Announces Neumifil™ is Efficacious
In an Established Model of COVID-19 Infection
Neumifil Binds with Equally High Affinity to Spike Proteins of Wuhan, UK and South African Variants
 
8
th March 2021 – St. Andrews, Scotland – Pneumagen Ltd, a biotech company developing a universal pan-viral intranasal drug for protection against respiratory tract infections (RTIs), today announced a further milestone in the development of Neumifil™ for the treatment of COVID-19. Utilizing a hamster model of COVID-19 infection, researchers showed Neumifil was efficacious, significantly reducing clinical signs and weight loss in animals infected with SARS-CoV-2.  
Pneumagen scientists located at the University of St. Andrews confirmed that Neumifil binds with equally high affinity to SARS-CoV-2 spike proteins from the Wuhan (Wuhan-Hu-1), UK (B.1.1.7) and South Africa (B.1.351) variants.  In further experiments, Pneumagen also demonstrated high affinity ....

South Africa , United Kingdom , South African , Douglas Thomson , Pneumagen Ltd , University Of St , Carbohydrate Binding Module , ஒன்றுபட்டது கிஂக்டம் , டக்ளஸ் தாம்சன் , பல்கலைக்கழகம் ஆஃப் ஸ்டம்ப் , கார்போஹைட்ரேட் பிணைப்பு தொகுதி ,

Pneumagen Announces Neumifil™ is Efficacious In an Established Model of COVID-19 Infection


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ST. ANDREWS, Scotland, March 8, 2021 /PRNewswire/
Pneumagen Ltd, a biotech company developing a universal pan-viral intranasal drug for protection against respiratory tract infections (RTIs), today announced a further milestone in the development of Neumifil™ for the treatment of COVID-19. Utilizing a hamster model of COVID-19 infection, researchers showed Neumifil was efficacious, significantly reducing clinical signs and weight loss in animals infected with SARS-CoV-2.  
Pneumagen scientists located at the University of St. Andrews confirmed that Neumifil binds with equally high affinity to SARS-CoV-2 spike proteins from the Wuhan (Wuhan-Hu-1), UK (B.1.1.7) and South Africa (B.1.351) variants. In further experiments, Pneumagen also demonstrated high affinity Neumifil binding to the ACE2 receptor, which is used by the SARS-CoV-2 virus to infect the host. ....

South Africa , United Kingdom , South African , Glycosylated Sarsco , Douglas Thomson , Scius Communications , Pneumagen Ltd , University Of St , Public Health England , Prnewswire Pneumagen Ltd , Carbohydrate Binding Module , Receptor Interactions , Cell Host , ஒன்றுபட்டது கிஂக்டம் , டக்ளஸ் தாம்சன் , பல்கலைக்கழகம் ஆஃப் ஸ்டம்ப் , பொது ஆரோக்கியம் இங்கிலாந்து , கார்போஹைட்ரேட் பிணைப்பு தொகுதி , ஏற்பி இடைவினைகள் , செல் தொகுப்பாளர் ,