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Landscape of HER2+ Metastatic Breast Cancer: Patient Overview

Expert oncologist Kevin Kalinsky, MD, MS, reviews a patient case of HER2+ metastatic breast cancer and highlights key findings in this disease setting. ....

Kevin Kalinsky , Improving Outcomes , Breast Cancer , Translating Evidence , Clinical Practice , Metastatic Breast Cancer , Her2 Breast Cancer , Her2 Positive , Thp Therapy , Cleopatra Trial , Cleopatra Regimen , Cns Metastasis , Cns Metastases , Whole Brain Radiation , Transaminases Elevation , Dose Reduction , Dose Hold , Her2 Targeted , Her2 Targeted Therapy ,

Cyteir Therapeutics Reports Fourth Quarter and Full Year 2022 Financial Results and Operational Highlights

Initial data from Phase 1 combination with capecitabine in advanced ovarian cancer are expected in mid-2023

Dose for the Phase 1 combination trials identified as 400mg daily

Ended 2022 with. | March 23, 2023 ....

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T-DXd shows high efficacy in HER2-positive breast cancer patients previously treated with T-DM1

Compared with capecitabine-based regimens, trastuzumab deruxtecan (T-DXd) led to higher response rates and longer survival in the third-line setting for patients with HER2-positive metastatic breast cancer previously treated with trastuzumab emtansine (T-DM1), according to results from the phase III DESTINY-Breast02 trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022. ....

San Antonio , United States , Ian Krop , Daiichi Sankyo , Genentech Roche , Emily Henderson , Puretech Health , Yale Cancer Center , Clinical Research , Bristol Myers Squibb , San Antonio Breast Cancer Symposium , Yale Cancer , Genomics Industry Focus , Seattle Genetics , Taiho Oncology , Breast Cancer , Central Nervous System , Clinical Trial , Interstitial Lung Disease , Ung Disease , Nervous System ,

Study estimates the cost-effectiveness of therapeutic alternatives

Giving standard chemotherapy drugs in a specific sequence for some types of metastatic breast cancer can help reduce overall costs and improve the value of care while preserving quality of life, according to a study led by UNC Lineberger Comprehensive Cancer Center and UNC Gillings School of Global Public Health researchers. ....

North Carolina , United States , Lineberger Katherinee Reeder Hayes , Stephanieb Wheeler , Emily Henderson , Gillings School Of Global Public Health , School Of Medicine , Lineberger Comprehensive Cancer Center , Health Policy Management , Comprehensive Cancer Center , Global Public Health , Health Policy , Gillings School , Global Public , Breast Cancer , Public Health ,

Drug combination yields highest response and longest survival rates for patients with pancreatic NETs

Very few treatment options are available to patients with advanced pancreatic neuroendocrine tumors (NETs), but researchers at the Yale Cancer Center and Yale New Haven Health's Smilow Cancer Hospital found that patients treated with a combination of capecitabine and temozolomide had longer progression-free survival rates than those treated with temozolomide alone. ....

United States , Pamela Kunz , Emily Henderson , Yale New Haven Health Smilow Cancer Hospital , Yale School Of Medicine , National Cancer Institute , National Clinical Trial Network , Yale Cancer Center , Yale New Haven Health , Smilow Cancer Hospital , American Society , Clinical Oncology , Yale School , Gastrointestinal Cancers , National Clinical Trial , Clinical Trial ,