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Intratumoural viral delivery improves glioblastoma survival

“Injecting a virus into a patient’s brain tumour” combined with immunotherapy improved glioblastoma survival outcomes in a clinical trial. ....

United States , Juan Fueyo , Candelaria Gomez Manzano , Frederick Lang , Merck Co , Division Of Cancer Medicine , Md Anderson Cancer Center , Nature Medicine , Cancer Medicine , Cancer Center , University Of Texas ,

Engineered Virus and Immunotherapy Combo Safe, Improves Glioblastoma Outcomes

Engineered Virus and Immunotherapy Combo Safe, Improves Glioblastoma Outcomes
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United States , Juan Fueyo , Frederick Lang , Candelaria Gomez Manzano , Merck Co , Dnatrix Inc , University Of Texas Md Anderson Cancer Center , University Of Toronto , Cancer Center , Nature Medicine ,

Combined delivery of engineered virus with im

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto. ....

University Of Texas , United States , Juan Fueyo , Candelaria Gomez Manzano , Frederick Lang , University Of Toronto , Dnatrix Inc , Merck Co , Anderson Cancer Center , Nature Medicine ,

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto. ....

United States , Frederick Lang , Juan Fueyo , Candelaria Gomez Manzano , Emily Henderson , University Of Toronto , Dnatrix Inc , Merck Co , University Of Texas Md Anderson Cancer Center , Cancer Center , Nature Medicine , Clinical Trial , Immune Response , Immune System ,