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"Evolution of Head and Neck Cutaneous Squamous Cell Carcinoma Nodal Sta" by Michael J.L. Hurrell, Tsu Hui Low et al.

Cutaneous squamous cell carcinoma of the head and neck (HNcSCC) is one of the commonest malignancies. When patients present with regional metastatic disease, treatment escalation results in considerable morbidity and survival is markedly reduced. Owing to the high incidence, Australian institutions have been at the forefront of advocating for reliable, accurate, and clinically useful staging systems that recognise the distinct biological characteristics of HNcSCC. As a result, an extensive body of literature has been produced over the past two decades, which has defined critical prognostic factors, critiqued existing staging systems, and proposed alternative staging models. Notwithstanding, a suitable staging system has proved elusive. The goal of cancer staging is to group patients according to cancer characteristics for which survival differs between groups (distinctiveness), consistently decreases with increasing stage (monotonicity), and is similar within a group (homogeneity). Des ....

United States , American Joint Committee On Cancer , American Joint Committee , Cancer Staging , Head And Neck Cancer , Ymphatic Metastasis , Squamous Cell Carcinoma ,