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How tumor stiffness alters immune cell behavi

How tumor stiffness alters immune cell behavi
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United States , Ilona Berestjuk , Grega Timblin , Rosae Menjivar , Bushra Samad , Alexander Muir , Kevin Tharp , Kelly Kersten , Roger Geiger , Alexisj Combes , Sanford Burnham Prebys , Stashko Connor , Fernandop Canale , Mary Kate Hayward , University Of California San Francisco , University Of Chicago , Microenvironment Program At Sanford Burnham Prebys , University Of Michigan , Method Of Research , Cancer Metabolism , Microenvironment Program , Sanford Burnham , Nature Cancer , California San Francisco , Ori Maller , Marina Pasca ,

Understanding the role of tumor-associated fibrosis in immunotherapy resistance

Immunotherapy is based on harnessing a person's own immune system to attack cancer cells. ....

United States , Ilona Berestjuk , Bushra Samad , Grega Timblin , Sanford Burnham Prebys , Fernandop Canale , Rosae Menjivar , Mary Kate Hayward , Stashko Connor , Kevin Tharp , Kelly Kersten , Alexisj Combes , Roger Geiger , Alexander Muir , University Of Chicago , Microenvironment Program At Sanford Burnham Prebys , University Of Michigan , University Of California San Francisco , Cancer Metabolism , Microenvironment Program , Sanford Burnham , Nature Cancer , California San Francisco , Ori Maller , Marina Pasca ,

Grouping tumors by 'immune archetypes' points the way to personalized immunotherapies

The UCSF researchers, led by first co-authors Alexis Combes, PhD, and Bushra Samad, MS, and senior author, Max Krummel, PhD, obtained tumor specimens from 78 UCSF clinicians, and surveyed 364 tumors biopsies from patients and categorized them into groups based on their immune microenvironment. ....

Bushra Samad , Roberte Smith , Max Krummel , Alexis Combes , Emily Henderson , Krummel Lab , Department Of Pathology , Incoming Assistant Professor , Endowed Chair , Experimental Pathology , Ancer Immunotherapy , Cancer Treatment , Immune System ,

Sorting Cancers by Microenvironment Potentially Shifts the View on Immunotherapy

Categorizing tumors into groups based on their immune microenvironment may improve immunotherapy and personalized medicine for cancer therapy. ....

United States , San Francisco , Bushra Samad , Roberte Smith , Max Krummel , Alexis Combes , University Of California , Immunoprofiler Initiative , Krummel Lab ,

Sorting Cancers by 'Immune Archetypes' May Offer New Approach For Precision Immunotherapies

Microscopic image of a human T cell. T cells are the focus of current immunotherapies, however, researchers found that tumors contain a wide range of ....

United States , San Francisco , Bushra Samad , Roberte Smith , Max Krummel , Alexis Combes , University Of California , Krummel Lab , Department Of Pathology , Endowed Chair , Experimental Pathology , Langley Porter Psychiatric Hospital ,