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Researchers reveal the inner workings of a viral DNA-packaging motor


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IMAGE: A trio of studies has revealed how a viral DNA packaging motor works, potentially providing insights for new therapeutics or synthetic molecular machines. Each of five proteins scrunches up in.
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Credit: Joshua Pajak, Duke University
DURHAM, N.C. - A group of researchers have discovered the detailed inner workings of the molecular motor that packages genetic material into double-stranded DNA viruses. The advance provides insight into a critical step in the reproduction cycle of viruses such as pox- herpes- and adeno-viruses. It could also give inspiration to researchers creating microscopic machines based on naturally occurring biomotors. ....

San Diego , United States , Marc Morais , Emilio Reyes Aldrete , Mark White , Wei Zhao , Gaurav Arya , Paul Jardine , Michael Woodson , Wei Zhang , Shelley Grimes , Paulj Jardine , Briana Kelch , Marka White , Brendanj Hilbert , Dwight Anderson , Marcc Morais , Joshua Pajak , Bryonp Mahler , De Shaw Research , National Institutes Of Health , Nucleic Acids Research , National Science Foundation , University Of Texas Medical Branch , Pittsburgh Supercomputing Center , San Diego Supercomputer Center ,