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Protein involved in removing Alzheimer's buildup linked to circadian rhythm | The Source


Brain protein helps explain link between circadian rhythm, Alzheimer’s disease
December 16, 2020
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Immune cells known as microglia (turquoise with red dots) surround a plaque of the Alzheimer’s protein amyloid (blue). The red dots indicate that the microglia are prepared to remove the potentially damaging plaque. Researchers at Washington University School of Medicine in St. Louis have discovered a protein that links the amyloid-removal process to the circadian clock. The protein, YKL-40, could help explain why people with Alzheimer’s frequently suffer from sleep disturbances, and provide a new target for Alzheimer’s therapies. (Image: Brian Lananna/School of Medicine) ....

Brianv Lananna , Erik Musiek , David Holtzman , Gretchenp Jones , Carlos Cruchaga , Anne Fagan , Brian Lananna School Of Medicine , Researchers At Washington University School Of Medicine , Department Of Neurology , Joanne Knight Alzheimer Disease Research Center , Washington University School , Science Translational Medicine , Joanne Knight Alzheimer , Disease Research , டேவிட் ஹோல்ட்ஸ்மேன் , அன்னே ஃபாகன் , ஆராய்ச்சியாளர்கள் இல் வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , துறை ஆஃப் நரம்பியல் , ஜொவந் நைட் முதுமறதி நோய் ஆராய்ச்சி மையம் , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி , அறிவியல் மொழிபெயர்ப்பு மருந்து , ஜொவந் நைட் முதுமறதி , நோய் ஆராய்ச்சி ,