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Business in Europe, Africa, Asia, and the Middle East is touched by adjustments in PRH’s international sales and marketing leadership, as Taylor & Francis partners with Jisc in the UK on open access. In Shanghai, January 12, one of the Japanese Tsutaya Books locations. Image – iStockphoto: Robert Way Cyrus Kheradi Announces Realignment As Publishing Perspectives readers know, the daily international wealth of personnel changes in book publishing are more than we’re normally able to cover. Today (April 16), however, we have word of a realignment in international sales and marketing teams at Penguin Random House USA, and these have such extensive reach into so many parts of the world publishing marketplace, that we want to mention them for our readers whose business will involve the key players. ....
Date Time Surprising Behavior of Transcription Factors Challenges Theories of Gene Regulation How cells develop and the diseases that arise when development goes wrong have been a decades-long research focus in the laboratory of Distinguished Professor of Biology Ellen Rothenberg. In particular, the lab studies the development of immune cells known as T cells, which act as “intelligence agents”-they circulate throughout the body, detect threats, and determine what kind of response the immune system should make. However, when the many stages of T cell development do not occur perfectly, leukemia occurs. “Many of the genes that we study in normal developing T cells are the same genes that, when regulated incorrectly, lead to the cells becoming T-cell leukemia,” says Rothenberg. “Understanding the precision of this process is really important. There’s also an interesting aspect of irreversibility: Some of the genes we study only have activity at a specific tim ....