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Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections Experts have uncovered a new molecular reason why fecal transplants are highly effective in treating infections such as C. difficile (a nasty bacteria that can infect the bowel), which could lead to more targeted treatments for this and other similar diseases. The study, published today in Gastroenterology, was led by experts from the University of Nottingham and Nottingham Trent University. Clostridium difficile, also known as C. difficile or C. diff, is a bacterium that can infect the bowel and cause diarrhea. The infection most commonly affects people who have recently been treated with antibiotics. It can spread easily to others. A stool transplant - or to give it its full title a fecal microbiota transplant (FMT) - aims to repopulate the patient s gut with the microbes from a healthy person, making it a successful therapy against

United kingdomNick markhamTanya monaghanBorden lacyAnna seekatzEmily hendersonNottingham trent universitySchool of medicineProf christine lee university of british columbiaDr dina kao university of albertaUniversity of nottinghamSchool of scienceNottingham trentClinical associate professorHonorary consultantAnne mclaren fellow