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KGO ABC World News Tonight With David Muir December 17, 2019 01:30:00

Swedens greetings. Enjoy your first payment on us when you lease a new volvo. Now through january 2nd. Tonight, the deadly storms as we come on the air. The tornadoes touching down. One tornado reportedly on the ground for 63 miles. Children put in ambulances and tonight, winter alerts across 20 states. Oklahoma, up through the northeast, cars and trucks off the highways. And tomorrow mornings commute, the storm system slamming cities in the east. Ginger zee timing it out. Also Breaking News at this hour involving boeing and their 737 max jets. After those two deadly crashes, just in tonight, boeing now halting production of its max jets. What does this mean for thousands of American Workers . Two midair scares tonight. The san diego to chicago flight making an Emergency Landing when flames are seen shooting from the ....

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Cartilage-like protein hydrogels engineered via entanglement

Load-bearing tissues, such as muscle and cartilage, exhibit high elasticity, high toughness and fast recovery, but have different stiffness (with cartilage being significantly stiffer than muscle)1–8. Muscle achieves its toughness through finely controlled forced domain unfolding–refolding in the muscle protein titin, whereas articular cartilage achieves its high stiffness and toughness through an entangled network comprising collagen and proteoglycans. Advancements in protein mechanics and engineering have made it possible to engineer titin-mimetic elastomeric proteins and soft protein biomaterials thereof to mimic the passive elasticity of muscle9–11. However, it is more challenging to engineer highly stiff and tough protein biomaterials to mimic stiff tissues such as cartilage, or develop stiff synthetic matrices for cartilage stem and progenitor cell differentiation12. Here we report the use of chain entanglements to significantly stiffen protein-based hydrogels w ....

International Cartilage Repair Society , Mechanical Design , Rubber Elasticity , Synovial Fluid , Sports Exerc , Soft Matter , Tissue Res , Cartilage Repair Society , Bone Joint ,