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Bold Therapeutics' BOLD-100 Effective In Vitro Against COVID-19 Variants


Bold Therapeutics Inc.
While viral mutations are inevitable, the potential for mutations to reduce the effectiveness of vaccines or potentially even render them ineffective is a source of considerable concern, particularly in countries with a vaccination-centric strategy. For example, the E484K mutation, first detected in both the South African (B.1.351) and Brazilian (B.1.1.28) variants – and more recently in the UK variant (B.1.1.7) – is a spike protein mutation that has been shown to be immune-evading, allowing previously infected patients to become reinfected and potentially allowing vaccinated patients to become infected. In just the past few weeks, a new Eek variant of concern (with both E484K and N501Y mutations) has emerged in Japan ....

United Kingdom , Western University , United States , British Columbia , South Africa , South African , E Russell Mcallister , Deena Hinshaw , University Of British Columbia , Bold Therapeutics Inc , Bold Therapeutics , Bold Therapeutic , Provincial Chief Medical Officer , National Research Council , Canada Industrial Research Assistance Program , ஒன்றுபட்டது கிஂக்டம் , மேற்கு பல்கலைக்கழகம் , ஒன்றுபட்டது மாநிலங்களில் , பிரிட்டிஷ் கொலம்பியா , ஏ ரஸ்ஸல் மக்யாலிஸ்டர் , தீனா ஹின்ஷா , பல்கலைக்கழகம் ஆஃப் பிரிட்டிஷ் கொலம்பியா , தைரியமான சிகிச்சை இன்க் , தைரியமான சிகிச்சை , மாகாண தலைமை மருத்துவ அதிகாரி , தேசிய ஆராய்ச்சி சபை ,