The findings of the mediation analyses underscore the important role that albuminuria plays in the nephropathy and related comorbidities associated with type 2 diabetes and CKD.
The two alternative formulas for calculating eGFR, the CKiD U25 and the European Kidney Function Consortium equations, showed higher levels of bias that resulted in underestimates of kidney function.
Analysis of glomerular filtration rates from more than 3000 US persons highlighted the broad variance that can occur between estimated and directly measured kidney values.
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