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In moving processes from bench to pilot and ultimately production fermentors, it is critical to have a reliable scaledown model. Scale-down models. ....
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Bioprocess researchers undertaking high-density mammalian, bacterial, or microbial cell culture separations can now benefit from a next-generation single-use, sterilized, closed-system BioProcess Container (BPC) designed to offer a highly efficient alternative for harvesting by centrifugation. The CentriPAK BPC, developed specifically for use with the Thermo Fisher Scientific Sorvall BIOS 16 centrifuge, enables optimal protection of critical sterile liquids from cross-contamination typically associated with reusable containers. The CentriPAK can be used to process culture volumes of between 3 L and 500 L, facilitating high-throughput and high-efficiency cell biomass or clarified supernatant harvesting to maximize laboratory productivity. Furthermore, there are no time-consuming, labor-intensive, and costly preparation and post-use cleaning steps involved. To ensure it meets the high standards expected in the bioprocessing industry, the unit is subject to thorough quality-control p ....
Mar 06 2021 Read 1934 Times Bioprocess researchers undertaking high-density mammalian, bacterial or microbial cell culture separations can now benefit from a next-generation single-use, sterilised, closed-system BioProcess Container (BPC) designed to offer a highly efficient alternative for harvesting by centrifugation. Developed specifically for use with the Thermo Scientific Sorvall BIOS 16 Centrifuge, the single-use, sterilised, closed-system Thermo Scientific CentriPAK BPC enables optimal protection of critical sterile liquids from cross-contamination typically associated with reusable containers. The CentriPAK BPC can be used to process culture volumes of between 3 and 500 L, facilitating high-throughput and high-efficiency cell biomass or clarified supernatant harvesting to maximise laboratory productivity. Furthermore, there are no time-consuming, labour-intensive and costly preparation and post-use cleaning steps involved. ....