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Cholesterol increases Covid-19 infectivity: Study - The Hindu BusinessLine

January 30, 2021
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It showed that dietary supplements and compounds vitamin D and possibly vitamins K and A could bind to the viral spike protein, reducing SARS-CoV-2 infectivity
A new study carried out by the University of Bristol added to the growing body of evidence that vitamin D and possibly vitamins K and A might help in preventing Covid-19 infection.
The study, published in the journal of the German Chemical Society Angewandte Chemie, has demonstrated that these dietary supplements and compounds could bind to the viral spike protein, reducing SARS-CoV-2 infectivity.
In contrast, cholesterol may increase the infectivity. This also explains why people with cholesterol-related issues run the risk of developing a serious disease. ....

Deborah Shoemark , Senior Research Associate Biomolecular , School Of Biochemistry , German Chemical Society Angewandte Chemie , University Of Bristol , Senior Research Associate , Biomolecular Modelling , Corona Virus , Covid 19 , Vitamin D , Sars Cov 2 , Spike Protein , மூத்தவர் ஆராய்ச்சி இணை உயிர் மூலக்கூறு , பள்ளி ஆஃப் உயிர் வேதியியல் , பல்கலைக்கழகம் ஆஃப் பிரிஸ்டல் , மூத்தவர் ஆராய்ச்சி இணை , உயிர் மூலக்கூறு மாடலிங் , கொரோனா வைரஸ் , வைட்டமின் ட , ஸ்பைக் ப்ரோடீந் , சர்வதேச பரவல் ,

How vitamins, steroids and potential antivirals might affect SARS-CoV-2

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Evidence is emerging that vitamin D - and possibly vitamins K and A - might help combat COVID-19. A new study from the University of Bristol published in the journal of the German Chemical Society
Angewandte Chemie has shown how they - and other antiviral drugs - might work. The research indicates that these dietary supplements and compounds could bind to the viral spike protein and so might reduce SARS-CoV-2 infectivity. In contrast, cholesterol may increase infectivity, which could explain why having high cholesterol is considered a risk factor for serious disease.
Recently, Bristol researchers showed that linoleic acid binds to a specific site in the viral spike protein, and that by doing so, it locks the spike into a closed, less infective form. Now, a research team has used computational methods to search for other compounds that might have the same effect, as potential treatments. They hope to prevent human cells becoming infected by preventing the vi ....

City Of , United Kingdom , Deborah Shoemark , Adrian Mulholland , Alison Derbenwick Miller , School Of Biochemistry , Bristol Synthetic Biology Centre , German Chemical Society Angewandte Chemie , Max Planck Bristol Centre For Minimal Biology , Senior Research Associate Biomolecular , Oracle For Research , University Of Bristol , Bristol School Of Chemistry , Senior Research Associate , Biomolecular Modelling , Derbenwick Miller , Vice President , Molecular Medicine , Max Planck Bristol Centre , Minimal Biology , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , பள்ளி ஆஃப் உயிர் வேதியியல் , பிரிஸ்டல் செயற்கை உயிரியல் மையம் , மூத்தவர் ஆராய்ச்சி இணை உயிர் மூலக்கூறு , ஆரக்கிள் க்கு ஆராய்ச்சி ,

Vitamins and other antiviral drugs may help combat COVID-19

Vitamins and other antiviral drugs may help combat COVID-19
Evidence is emerging that vitamin D - and possibly vitamins K and A - might help combat COVID-19. A new study from the University of Bristol published in the journal of the German Chemical Society Angewandte Chemie has shown how they - and other antiviral drugs - might work.
The research indicates that these dietary supplements and compounds could bind to the viral spike protein and so might reduce SARS-CoV-2 infectivity. In contrast, cholesterol may increase infectivity, which could explain why having high cholesterol is considered a risk factor for serious disease. ....

Deborah Shoemark , Adrian Mulholland , Alison Derbenwick Miller , Emily Henderson , Senior Research Associate Biomolecular , School Of Biochemistry , Oracle For Research , German Chemical Society Angewandte Chemie , University Of Bristol , Bristol School Of Chemistry , Senior Research Associate , Biomolecular Modelling , Derbenwick Miller , Vice President , எமிலி ஹென்டர்சன் , மூத்தவர் ஆராய்ச்சி இணை உயிர் மூலக்கூறு , பள்ளி ஆஃப் உயிர் வேதியியல் , ஆரக்கிள் க்கு ஆராய்ச்சி , பல்கலைக்கழகம் ஆஃப் பிரிஸ்டல் , பிரிஸ்டல் பள்ளி ஆஃப் வேதியியல் , மூத்தவர் ஆராய்ச்சி இணை , உயிர் மூலக்கூறு மாடலிங் , துணை ப்ரெஸிடெஂட் ,

Vitamin D and other antiviral drugs might help combat COVID-19

Vitamin D and other antiviral drugs might help combat COVID-19
How vitamins, steroids, and potential antivirals might affect SARS-CoV-2?
Stock illustration image of the spike glycoprotein
A new study by the University of Bristol suggests that Vitamin D and other antiviral drugs might help combat COVID-19. The study demonstrates that these dietary supplements and compounds could bind to the viral spike protein, thus may decrease SARS-CoV-2 infectivity.
Conversely, cholesterol may increase infectivity, which could clarify why having elevated cholesterol is considered a risk factor for severe disease.
In their study, scientists showed that linoleic acid sticks to a particular region in the viral spike protein, locking the spike into a closed, less infective form. ....

Deborah Shoemark , Adrian Mulholland , Senior Research Associate Biomolecular , School Of Biochemistry , University Of Bristol , Bristol School Of Chemistry , Senior Research Associate , Biomolecular Modelling , மூத்தவர் ஆராய்ச்சி இணை உயிர் மூலக்கூறு , பள்ளி ஆஃப் உயிர் வேதியியல் , பல்கலைக்கழகம் ஆஃப் பிரிஸ்டல் , பிரிஸ்டல் பள்ளி ஆஃப் வேதியியல் , மூத்தவர் ஆராய்ச்சி இணை , உயிர் மூலக்கூறு மாடலிங் ,

Bristol University study reveals vitamins could be used to fight Covid

Bristol University study reveals vitamins could be used to fight Covid
Vitamins could help combat Covid infections
14:42, 29 JAN 2021
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A new study by Bristol University has revealed how vitamins, steroids and antiviral drugs could be used to reduce covid infections. ....

City Of , United Kingdom , Deborah Shoemark , Adrian Mulholland , School Of Biochemistry , Bristol Synthetic Biology Centre , Bristol University , Max Planck Bristol Centre For Minimal Biology , Senior Research Associate Biomolecular , University Of Bristol , Bristol School Of Chemistry , Senior Research Associate , Biomolecular Modelling , Molecular Medicine , Max Planck Bristol Centre , Minimal Biology , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , பள்ளி ஆஃப் உயிர் வேதியியல் , பிரிஸ்டல் செயற்கை உயிரியல் மையம் , பிரிஸ்டல் பல்கலைக்கழகம் , மூத்தவர் ஆராய்ச்சி இணை உயிர் மூலக்கூறு , பல்கலைக்கழகம் ஆஃப் பிரிஸ்டல் , பிரிஸ்டல் பள்ளி ஆஃப் வேதியியல் , மூத்தவர் ஆராய்ச்சி இணை , உயிர் மூலக்கூறு மாடலிங் ,