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"Colistin and carbapenems as last-resort antibiotics: Challenging envir" by Elipsha Sharma, Yan Chen et al.

Colistin and carbapenems, vital last-resort antibiotics against severe bacterial infections unresponsive to common drugs, pose a threat when resistance develops as it may leads to complete antibiotic ineffectiveness. The estimation and quantification of colistin and carbapenems in environmental samples is challenging due to their low concentrations, complex structures, stability issues, and potential interference from other substances. Despite known side-effects, the biological impacts of their residues recirculated in the environment has not yet been evaluated. This review provides an in-depth analysis of these two critical drugs by exploring their chemical and biological properties and current detection. This is based on 41 analytical studies on their quantitation methods, with 7 studies being from environmental matrices and the rest being from biological matrices. Reverse-phased chromatography and high-performance liquid chromatography tandem mass spectrometry are the main instrumen ....

Antibiotic Residues , Antibiotic Resistance , Biological Matrices , Environmental Matrices , Environmental Surveillance , Plc Tandem Mass Spectrometry , Everse Phased Chromatography ,

LC-MS reversed-phase and HILIC methods for separations

Novel screening approach for comparing LC-MS reversed-phase and HILIC methods for separations in biological matrices ....

Materials Technology , Application Note , Advanced Materials Technology , Gc Ms , Biological Matrices ,

Challenges of Cannabis Analysis and Impacts on Driving and Public Health


Challenges of Cannabis Analysis and Impacts on Driving and Public Health
Thought LeadersDr. Madeleine SwortwoodAssistant Professor, Department of ForensicsSam Houston State University
In this interview, Dr. Madeleine Swortwood of Sam Houston State University talks to News-Medical Life Sciences about the symposium she will lead at Pittcon this year on the analytical challenges of cannabis and its impacts on driving and public health.
What role does cannabis play in 2021, especially in the realm of public health?
With increased medicinal and recreational use, we really need to have a solid understanding of how this is going to impact drug-impaired driving, workplace safety and even accidental toxic exposures. ....

United States , Florida International University , Erin Karschner , Madeleine Swortwood , Hquality Shutterstock , Daniel Chetroni Shutterstock , Marilyn Huestis , National Institute On Drug Abuse , American Academy Of Forensic Sciences , Drug Administration Forensic Chemistry Center , National Institutes Of Health , Duquesne University , Sam Houston State University , Dade Medical Examiner Toxicology Laboratory , Society Of Forensic Toxicologists , Life Sciences , Department Of Forensicssam Houston State University , Madeleine Swortwoodassistant Professor , Forensicssam Houston State , News Medical Life Sciences , Quantifying Cannabinoids , Biological Matrices , Legal Cannabis , Sam Houston , Daniel Chetroni , Forensic Toxicologists ,