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Nottingham Research Centre, US Firm Partner for Ovarian Cancer Drugs

Nottingham Research Centre, US Firm Partner for Ovarian Cancer Drugs
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United Kingdom , City Of , United States , Farid Suleman , Debanu Das , Srinivasan Madhusudan , Lloyds Tsb , Biodiscovery Institute , Royal College Of Obstetrics , Clore Social Leadership Programme , A University Of Nottingham , National Cancer , Naaz Coker Ovarian Cancer Research Centre , Small Business Innovation Research , British Refugee Council , Professor Srinivasan , National Cancer Institute Supported , Clinical Director , General Manager , Royal College , Clore Social Leadership ,

Systematic approaches to C-lignin engineering in Medicago truncatula | Biotechnology for Biofuels and Bioproducts

C-lignin is a homopolymer of caffeyl alcohol present in the seed coats of a variety of plant species including vanilla orchid, various cacti, and the ornamental plant Cleome hassleriana. Because of its unique chemical and physical properties, there is considerable interest in engineering C-lignin into the cell walls of bioenergy crops as a high-value co-product of bioprocessing. We have used information from a transcriptomic analysis of developing C. hassleriana seed coats to suggest strategies for engineering C-lignin in a heterologous system, using hairy roots of the model legume Medicago truncatula. We systematically tested strategies for C-lignin engineering using a combination of gene overexpression and RNAi-mediated knockdown in the caffeic acid/5-hydroxy coniferaldehyde 3/5-O-methyltransferase (comt) mutant background, monitoring the outcomes by analysis of lignin composition and profiling of monolignol pathway metabolites. In all cases, C-lignin accumulation required strong dow ....

United States , Bioanalytical Facility Of The Biodiscovery Institute , University Of North Texas , Gene Universal , Jing Ke Weng , Minelute Cleanup Kit , Life Technologies , Bioanalytical Facility , Biodiscovery Institute , North Texas , Triple Quadrupole ,

University Of Nottingham secures funding for research into advanced prostate cancer

Scientists at the University of Nottingham have received more than £1million in support for research that aims to develop new treatments for advanced prostate cancer and to train the next generation of prostate cancer research leaders.The work, being ....

United Kingdom , West Bridgford , City Of , United States , Simon Grieveson , Corinne Woodcock , Robert Oldroyd , Nigel Mongan , Jennie Jeyapalan , Research Innovation Awards Rias , Prostate Cancer Foundation , Biodiscovery Institute , John Black Charitable Foundation , University Of Nottingham , Research At Prostate Cancer United Kingdom , Professor Nigel Mongan , Drs Jennie Jeyapalan , Prostate Cancer United Kingdom , John Black Charitable , Cancer United Kingdom , Research Innovation Awards , Assistant Director , Professor Mongan , Prostate Cancer United ,

University Secures Major Funding for Advanced Prostate Cancer Research

University Secures Major Funding for Advanced Prostate Cancer Research
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United Kingdom , West Bridgford , City Of , United States , Corinne Woodcock , Jennie Jeyapalan , Robert Oldroyd , Nigel Mongan , Simon Grieveson , Research At Prostate Cancer United Kingdom , Prostate Cancer Foundation , Research Innovation Awards Rias , John Black Charitable Foundation , Biodiscovery Institute , University Of Nottingham , Professor Nigel Mongan , Drs Jennie Jeyapalan , Prostate Cancer United Kingdom , John Black Charitable , Cancer United Kingdom , Research Innovation Awards , Assistant Director , Professor Mongan , Prostate Cancer United ,

Scientists to benefit from multimillion funding boost for biofilms studies

Scientists to benefit from multimillion funding boost for biofilms studies
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United Kingdom , City Of , Jo Slater Jefferies , School Of Life Sciences , University Of Nottingham Co , Biodiscovery Institute , National Biofilms Innovation Centre , University Of Nottingham , Health Sciences , Sciences Research Council , Biological Sciences Research Council , Innovate United , Biofilm Week , Nottingham Co Director , Life Sciences , Innovate United Kingdom , Professor Slater Jefferies ,