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Patients May Prefer Opioid Addiction Medicine Injected Weekly or Monthly to Daily Pills

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It may be easier for patients who take buprenorphine for opioid use disorder to stick with treatment if they receive a weekly or monthly injected version of the drug instead of a daily oral form of this medicine, according to a study published in May 2021 in
For the study, researchers compared what’s known as subcutaneous depot buprenorphine, a slow-release version of the drug that’s injected weekly or monthly into the buttocks, thigh, abdomen, or upper arm, to what’s known as sublingual buprenorphine, a daily oral version that dissolves when placed under the tongue.
A total of 119 adults seeking treatment for opioid use disorder were randomly assigned to receive injected or oral buprenorphine for 24 weeks. At the end of the trial, participants completed patient satisfaction surveys that were scored from 0 to 100 points, with higher scores indicating a better experience. ....

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U.S. Drug Overdose Deaths Hit Record During COVID-19 Pandemic

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Fatalities tied to synthetic opioids and illegal fentanyl climbed 38.4 percent in the 12 months ending in May 2020, compared with the same period ending in May 2019, according to the CDC. The spike in overdose deaths tied to these substances was even steeper in several parts of the country, almost doubling in 10 Western states.
In addition, overdose deaths involving psychostimulants such as methamphetamine increased by 34.8 percent, exceeding the total number of fatalities involving cocaine. Overdose deaths from cocaine climbed 26.5 percent, likely due to combined use with illegally manufactured fentanyl or heroin, the CDC reports.
There are likely several reasons why drug overdose deaths have surged since the onset of the COVID-19 pandemic, says Alana Vivolo-Kantor, PhD, lead health scientist at the division of overdose prevention at the CDC in Atlanta. These include a larger supply of illegal drugs, reduced access to addiction and overdose tre ....

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