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Researchers decipher enzyme scissors of intestinal microbes

Researchers decipher enzyme scissors of intestinal microbes
sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.

Bernd Nidetzky ,

Researchers decipher enzyme scissors of intestinal microbes

Researchers decipher enzyme scissors of intestinal microbes
phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.

Bernd Nidetzky , Martin Pfeiffer , Johannes Bitter , Nature Communications , Institute Of Biotechnology , University Of Graz , Biochemical Engineering , Graz University , Medical University ,

Accurate prediction of protein structures and interactions using a three-track neural network

Accurate prediction of protein structures and interactions using a three-track neural network
sciencemag.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencemag.org Daily Mail and Mail on Sunday newspapers.

United States , Doug Tischer , Mareike Monschein , Naozumi Hiranuma , Davide Kim , Bernd Nidetzky , David Juergens , Eric Horvitz , Deepmind Alphafold , Luki Goldschmidt , Wendy Schmidt , National Institute Of Health , Global Challenges Research Fund , Austrian Science Fund , Science Technology Facilities Council , National Science Foundation Cyberinfrastructure , Welch Foundation , Mathers Foundation , Protein Data Bank , Washington Research Foundation , Synchrotron Techniques For African Research , Canadian Institute Of Health Research , Graz University Of Technology , Critical Assessment , Continuous Automated Model Evaluation , Sanaa Mansoor ,

RNA basic building block produced biocatalytically for the first time

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IMAGE: The Graz researchers are the first in the world to demonstrate YeiN , an enzyme that is a suitable biocatalyst for the production of C-nucleosides, the basic building blocks of RNA..
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Credit: Lunghammer - TU Graz
Due to the COVID 19 pandemic and the associated intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is experiencing an enormous increase in interest. Natural and synthetic nucleosides have an antiviral effect and can act as building blocks of ribonucleic acids (RNA). When incorporated into RNA, novel interactions within the macromolecule result with positive consequences for stability and biological effectiveness. ....

Martin Pfeiffer , Bernd Nidetzky , Nature Communications , Austrian Centre Of Industrial Biotechnology , Head Of The Institute Biotechnology , Austrian Science Fund , Graz University Of Technology , Graz University , Austrian Centre , Industrial Biotechnology , Bioprocess Engineering , Scientific Director , Reversec Glycosidase , மார்டின் ஃபைஃபர் , இயற்கை தகவல்தொடர்புகள் , ஆஸ்திரேலிய மையம் ஆஃப் தொழில்துறை உயிரி தொழில்நுட்பவியல் , தலை ஆஃப் தி நிறுவனம் உயிரி தொழில்நுட்பவியல் , ஆஸ்திரேலிய அறிவியல் நிதி , க்ர்யாஸ் பல்கலைக்கழகம் ஆஃப் தொழில்நுட்பம் , க்ர்யாஸ் பல்கலைக்கழகம் , ஆஸ்திரேலிய மையம் , தொழில்துறை உயிரி தொழில்நுட்பவியல் , அறிவியல் இயக்குனர் ,

First enzyme-driven biocatalytic production of nucleic acid building blocks

First enzyme-driven biocatalytic production of nucleic acid building blocks
Researchers from TU Graz and acib succeed in the first enzyme-driven biocatalytic synthesis of nucleic acid building blocks. This facilitates the development of antiviral agents and RNA-based therapeutics.
Due to the COVID 19 pandemic and the associated intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is experiencing an enormous increase in interest. Natural and synthetic nucleosides have an antiviral effect and can act as building blocks of ribonucleic acids (RNA). When incorporated into RNA, novel interactions within the macromolecule result with positive consequences for stability and biological effectiveness. ....

Martin Pfeiffer , Bernd Nidetzky , Emily Henderson , Nature Communications , Austrian Centre Of Industrial Biotechnology , Head Of The Institute Biotechnology , Graz University Of Technology , Graz University , Austrian Centre , Industrial Biotechnology , Bioprocess Engineering , Scientific Director , மார்டின் ஃபைஃபர் , எமிலி ஹென்டர்சன் , இயற்கை தகவல்தொடர்புகள் , ஆஸ்திரேலிய மையம் ஆஃப் தொழில்துறை உயிரி தொழில்நுட்பவியல் , தலை ஆஃப் தி நிறுவனம் உயிரி தொழில்நுட்பவியல் , க்ர்யாஸ் பல்கலைக்கழகம் ஆஃப் தொழில்நுட்பம் , க்ர்யாஸ் பல்கலைக்கழகம் , ஆஸ்திரேலிய மையம் , தொழில்துறை உயிரி தொழில்நுட்பவியல் , அறிவியல் இயக்குனர் ,