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The telomere tumult: meaning and metrics in population studies

The telomere tumult: meaning and metrics in population studies
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Vasiliki Bountziouka , Us National Institutes Of Health , Research Council Of Norway , The Lancet Healthy Longevity , United Kingdom , Healthy Longev , United Kingdom Biobank , Kingdom Biobank , Soc Open Sci , Mol Genet , Behav Immun , Research Council ,

Frontiers | Factors Associated With Severity of Delirium Complicating COVID-19 in Intensive Care Units

The clinical outcome of the disease provoked by the Sars-CoV-2 infection, COVID-19, is largely due to the development of interstitial pneumonia accompanied by an Acute Respiratory Distress Syndrome (ARDS), often requiring ventilatory support therapy in Intensive Care Units (ICUs). Current epidemiologic evidence is demonstrating that the COVID-19 prognosis is significantly influenced by its acute complications. Among these, delirium figures as one of the most frequent and severe, especially in the emergency setting, where it shows a significantly negative prognostic impact. In this regard, the aim of our study is to identify clinical severity factors of delirium complicating COVID-19 related-ARDS. We performed a comparative and correlation analysis using demographics, comorbidities, multisystemic and delirium severity scores and anti-delirium therapy in two cohorts of ARDS patients with delirium respectively due to COVID-19 (n=40) or other medical conditions (n=39). Our results indicate ....

United States , Sachsen Anhalt , Ospedale Maggiore Policlinico , Paolo Brambilla , Anesth Analg , Granda Ospedale Maggiore Policlinico , American Psychiatric Association , Definition Task , Group Correlations , World Health Organization , Ethics Committee Milan Area , Care Study Group , Brain Behav Immun Health , American Psychiatric Publishing Inc , Ethics Committee Of The Fondazione , Intensive Care Units , Respiratory Syndrome Coronavirus , Middle East Respiratory Syndrome Coronavirus , Acute Respiratory Distress Syndrome , Psychiatry Unit , Ospedale Maggiore , Ethics Committee , Ospedale Maggiore Policlinico Intensive Care Unit , Organ Failure Assessment , Confusion Assessment Method , Microsoft Excel ,