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Sleep Apnea Alters Gene Activity Patterns Over 24 Hours

The low blood oxygen levels of obstructive sleep apnea cause widespread changes in gene activity throughout the day, according to a new study. ....

United States , Bala Sc Koritala , David Smith , Cincinnati Children Hospital Medical Center , Cincinnati Children , Hospital Medical Center ,

Mice study shows how obstructive sleep apnea may affect gene activity throughout the day

The low blood oxygen levels of obstructive sleep apnea cause widespread changes in gene activity throughout the day, according to a new study in the open-access journal PLOS Biology by David Smith of Cincinnati Children's Hospital Medical Center, US, and colleagues. ....

United States , David Smith , Danielle Ellis , Bala Sc Koritala , Cincinnati Children Hospital Medical Center , Cincinnati Children , Hospital Medical Center , Obstructive Sleep Apnea , Obstructive Sleep Apnea , Sleep Apnea , Ene Expression ,

Obstructive Sleep Apnea Causes Widespread Gene Disruption in Mice throughout the Day

Findings provide insight into pathophysiological mechanisms that be associated with end-organ damage in patients chronically exposed to intermittent hypoxia ....

United States , Bala Sc Koritala , David Smith , Cincinnati Children Hospital Medical Center , Cincinnati Children , Hospital Medical Center ,

Research finds obstructive sleep apnea alters mice gene activity

Miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers. ....

United States , David Smith , Bala Sc Koritala , Cincinnati Children Hospital Medical Center , Cincinnati Children , Hospital Medical Center , Obstructive Sleep Apnea ,

How night shift work increases cancer risk revealed in new study -- Health & Wellness -- Sott.net

© Bala Koritala
A night shift schedule is associated with increased DNA damage and misalignment of the DNA repair mechanism, providing a possible explanation for the elevated risk of cancer in night shift workers.New clues as to why night shift workers are at increased risk of developing certain types of cancer are presented in a new study conducted at Washington State University Health Sciences Spokane.
Published online in the
Journal of Pineal Research, the study involved a controlled laboratory experiment that used healthy volunteers who were on simulated night shift or day shift schedules. Findings from the study suggest that night shifts disrupt natural 24-hour rhythms in the activity of certain cancer-related genes, making night shift workers more vulnerable to damage to their DNA while at the same time causing the body s DNA repair mechanisms to be mistimed to deal with that damage. ....

Hugh Mitchell , Van Dongen , Jason Mcdermott , Bala Sc Koritala , Kenneth Porter , Hans Van Dongen , Justin Teeguarden , Rajendra Gajula , Mugimane Manjanatha , Osama Arshad , Bala Koritala , Tarana Arman , Shobhan Gaddameedhi , Performance Research Center , Elsons Floyd College Of Medicine , Pacific Northwest National Laboratory Biological Sciences Division , Carolina State University Biological Sciences Department , Journal Of Pineal Research , Human Health , Washington State University Health Sciences Spokane , College Of Pharmacy , Health Sciences Spokane , Washington State University Health Sciences , Pineal Research , World Health Organization , International Agency ,