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Cornell University-led biomedical initiatives get NIH funding

Jack Freed, the Frank and Robert Laughlin Professor of Physical Chemistry Emeritus in the College of Arts and Sciences (A&S), has received two grants totaling $7.8 million over five years from the National Institutes of Health to use electron-spi ....

Brian Crane , National Biomedical Resource For Advanced , National Institutes Of Health , Baker Lab On Cornell Ithaca , College Of Arts , Jack Freed , Robert Laughlin Professor , Physical Chemistry Emeritus , National Institutes , National Biomedical Resource , Baker Lab , Viral Membrane Fusion , Membrane Interactions , Intrinsically Disordered Protein ,

Flatiron Institute Using Argonne HPC to Design Peptide-based Drugs with Quantum Mechanics - High-Performance Computing News Analysis

A team from the Flatiron Institute is leveraging supercomputing resources from the Argonne Leadership Computing Facility to advance the design of peptides [.] ....

United States , Vikram Mulligan , University Of Washington Baker Lab , Flatiron Institute , Baker Lab , Small Molecule Drugs , New Dehli ,

ALCF Supercomputers Help Design of Peptide-Based Drugs with Quantum Mechanics

ALCF Supercomputers Help Design of Peptide-Based Drugs with Quantum Mechanics
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United States , Department Of Energy , District Of Columbia , Vikram Mulligan , Office Of Science , Flatiron Institute , Argonne National Laboratory , University Of Washington Baker Lab , Us Department Of Energy , Argonne Leadership Computing Facility , National Laboratory , Baker Lab , New Dehli ,

Reinforcement learning: From board games to p

An AI strategy proven adept at board games like Chess and Go, reinforcement learning, has now been adapted for a powerful protein design program. The results show that reinforcement learning can do more than master board games. When trained to solve long-standing puzzles in protein science, the software excelled at creating useful molecules. In one experiment, proteins made with the new approach were found to be more effective at generating useful antibodies in mice than were previous methods. If this method is applied to the right research problems, it likely could accelerate progress in a variety of scientific fields. ....

Christoffer Norn , Ian Haydon , David Baker , Annie Dosey , Isaacd Lutz , Andrewj Borst , Shunzhi Wang , Hannele Ruohola Baker , Neilp King , Uw Medicine Institute For Protein Design , Institute For Protein Design , Uw Medicine Institute For Stem Cell , Breakthrough Prize In Life Sciences , Department Of Energy , University Of Washington , Uw School Of Medicine , Method Of Research , Lawrence Berkeley National Laboratory , National Institutes Of Health , Baker Lab , Novo Nordisk Foundation , Stem Cell , Regenerative Medicine , National Institutes , Open Philanthropy Project , Audacious Project ,