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Why can SARS-CoV-2 infection cause neurological and cardiovascular symptoms? Research looking at the pathophysiology behind coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is ongoing. A team of researchers from Columbia University Vagelos College of Physicians & Surgeons, USA, present results linking oxidative stress and the activation of a biochemical pathway associated with Alzheimer’s disease to SARS-CoV-2 infection. “In this study, we propose a potential mechanism that may contribute to systemic organ failure caused by SARS-CoV-2: defective Ca 2+ regulation and its downstream signaling,” wrote the researchers. “Of particular interest is that leaky RyR2 channels in the brain were associated with activation of neuropathological pathways that are also found in the brains of Alzheimer’s Disease patients.” ....
We re staring at screens more during COVID. How might that affect our eyes? Brendan O’Sullivan FacebookTwitterEmail 1of5 Student Salvatore Leone spends a lot of time in front of a screen.Sean O’Sullivan / ContributedShow MoreShow Less 2of5 Student Salvatore Leone spends a lot of time in front of a screen.Sean O’Sullivan / ContributedShow MoreShow Less 3of5 4of5 Jess Brij-Raj is a sophomore media studies and public relations major at Quinnipiac University in Hamden.Jess Brij-Raj / ContributedShow MoreShow Less 5of5 School supplies, a monitor and food fill the surface of the wooden desk where Salvatore Leone spends the majority of his time. He is, after all, a college student, and screens dominate his life. ....
Researchers immunoengineer nanobead system for circulating tumor cell detection A team of researchers has immunoengineered a nanobead system for the isolation and detection of circulating tumor cells (CTCs). A report on their research has been released on the Cancerous tissues shed free tumor cells – known as CTCs – into the peripheral blood. CTCs are associated with 90% of cancer-related deaths. They are therefore considered prognostic biomarkers in tumor metastasis and cancer diagnostics. However, the lack of an efficient commercial test has limited this approach. An interdisciplinary team – from Harvard University in the U.S. and the Second Military University and Tongji University in China – has designed and obtained a method to detect these CTCs from the buffer or peripheral blood. ....