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Mettl3 guides CD8 T cells to eliminate infected cells with maximum efficiency

This study is led by Dr. Shuyang Yu (College of Biological Sciences, China Agricultural University), Dr. Jingyu Xu (The Collaborative Innovation Center of Tissue Damage Repair and Regeneration Medicine of Zunyi Medical University) and Dr. Xuguang Du (College of Biological Sciences, China Agricultural University) and illustrated the key role of Mettl3 in CD8 T cell response during acute infection model. ....

Jingyu Xu , Xuguang Du College Of Biological Sciences , Regeneration Medicine Of Zunyi Medical University , Science China , Shuyang Yu College Of Biological Sciences , Collaborative Innovation Center , China Agricultural University , Biological Sciences , Tissue Damage Repair , Regeneration Medicine , Zunyi Medical University , Cell Cycle ,

GFH009 disrupts growth signals and triggers apoptosis in hematologic malignancies

A new research paper was published in Oncotarget's Volume 14 on December 20, 2023, entitled, "The pharmacodynamic and mechanistic foundation for the antineoplastic effects of GFH009, a potent and highly selective CDK9 inhibitor for the treatment of hematologic malignancies." ....

Qiang Lu , Lili Tang , Fubo Xie , Siyuan Le , Fusheng Zhou , Jinmin Ren , Dragan Cicic , Genfleet Therapeutics Inc , Sellas Life Sciences Group , Jiong Lan , Genfleet Therapeutics , Cell Cycle , N Vivo , Protein Expression ,

Programmed Cell Death's Origins Date Back 1.8 Billion Years

Apoptosis, often referred to as programmed cell death, is a fundamental process crucial to the growth and development of multicellular organisms. ....

Biophysics Of The Polish Academy Sciences , Institute Of Biochemistry , Genome Biology , Polish Academy , Ell Death ,

Mauritius sea sponge produces chemicals that can kill liver cancer cells – findings are a positive first step

A marine sponge from Mauritius has shown potential as the source of compounds that kill liver cancer cells. ....

Atlantic Ocean , University Of Mauritius , Pacific Ocean , Alexander Kagansky , Ranjeet Bhagooli , Vidushi Neergheen , Indian Ocean , Theeshan Bahorun , University Of Edinburgh , Caribbean Sea , Drug Discovery , Marine Sponges , Programmed Cell Death ,

Cell death is essential to your health − an immunologist explains when cells decide to die with a bang or take their quiet leave

Your cells die to keep you alive. Cell death does everything from fighting cancer cells and pathogens to forming your fingers and toes. ....

Black Death , Autoimmune Diseases , Cell Biology , Cellular Senescence , Infectious Diseases , Programmed Cell Death ,