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Bayer Falls Short in Bid to Beat Eliquis in Afib, But Key Stroke Study Continues

An independent data monitoring committee concluded Bayer’s experimental drug for atrial fibrillation would not be more effective than Eliquis, a blockbuster product currently used for the indication. Consequently, Bayer decided to stop that Phase 3 test for the once-daily oral small molecule. ....

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Abelacimab Demonstrates Significant Reduction in Bleeding vs Rivaroxaban in Patients With Atrial Fibrillation

The AZALEA-TIMI 71 randomized trial evaluated the safety and tolerability of 2 blinded doses of the novel factor XI inhibitor abelacimab compared with open-label rivaroxaban. ....

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Race to Develop Safer Anticoagulants: Anthos Blood Thinner Demonstrates Reduced Bleeding Risk

Race to Develop Safer Anticoagulants: Anthos Blood Thinner Demonstrates Reduced Bleeding Risk
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Anthos blood thinner bests Xarelto on safety in mid-stage study

BioPharma ....

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Anthos Therapeutics' Novel Dual-Acting Factor XI/XIa Inhibitor, Abelacimab 150 mg, Demonstrated a 67% Reduction in the Primary Endpoint of Major or Clinically Relevant Non-Major Bleeding Compared with Rivaroxaban in Patients with Atrial Fibrillation

CAMBRIDGE, Mass. (BUSINESS WIRE) Nov 12, 2023 ....

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