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Discovery of role of a key gene in development of ALS

Discovery of role of a key gene in development of ALS
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Kessen Patten , Anna Sforza Djoukhadjian Research Chair , Communications Biology , Anna Sforza Djoukhadjian Research , தகவல்தொடர்புகள் உயிரியல் ,

Imaging zebrafish movements in 3D to better understand ALS disease


Credit: Christian Fleury (INRS)
An interdisciplinary team of the Institut national de la recherche scientifique (INRS) used an innovative imaging technique for a better understanding of motor deficits in Amyotrophic Lateral Sclerosis (ALS). The researchers were able to follow the escape behaviour of normal and disease zebrafish models, in 3D. Their results have recently been published in
Optica, the flagship journal of the Optical Society (OSA).
Professor Jinyang Liang, expert in ultra-fast imaging and biophotonics, joined an effort with Professor Kessen Patten, specialist in genetics and neurodegenerative diseases. The two groups were able to track the position of zebrafish in real time and capture the 3D motion, using a special imaging technique called dispersion-eliminated coded-aperture light field, or DECALF. ....

Kessen Patten , Armand Frappier Sant , Jingdan Liu , Charlotte Zaouter , Shunmooguma Patten , Xianglei Liu , Terre Environnement , Jinyang Liang , Anna Sforza Djoukhadjian Research , Optical Society , Engineering Research Council Of Canada , Natural Sciences , Canada Foundation For Innovation , Amyotrophic Lateral Sclerosis , Professor Kessen Patten , Professor Liang , Engineering Research Council , Canada Foundation , Fonds De Recherche , Anna Sforza Djoukhadjian Research Chair , Quebec City , Eau Terre Environnement , Urbanisation Culture Soci , Chemistry Physics Materials Sciences , Medicine Health , ஆர்மண்ட் ப்றப்பிேர் சந்த் ,