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Cells resistant to treatment already present before diagnosis of adult leukaemia


Credit: IRB Barcelona
T-cell acute lymphoblastic leukaemia (T-ALL) is a cancer of the blood that affects mainly children, but also less frequently adults. In adults, although the response to treatment might be initially positive, relapses are common and have a poor prognosis.
A collaborative project between IRB Barcelona s Biomedical Genomics lab, headed by ICREA researcher Núria López-Bigas, Anna Bigas group at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar), and Josep Maria Ribera s lab at the Josep Carreras Leukaemia Research Institute (IJC) has discovered that the cells responsible for resistance to T-ALL treatment in adults are already present in the tumours before diagnosis. ....

Comunidad Autonoma De Cataluna , Josep Mar , Triasi Pujol , Anna Bigas , Josep Maria Ribera , Research Group , Haematology Service , Josep Carreras Leukaemia Research Institute , Biomedical Genomics , Anna Biga , Hospital Del Mar Medical Research Institute , Hospital Del Mar , Santiago Gonz , Germans Trias , Pujol Hospital , Stem Cell , காமுனிடட தன்னாட்சி டி கடலுள் , ஜோசப் மார் , அண்ணா போகஸ் , ஜோசப் மரியா ரிபேரா , ஆராய்ச்சி குழு , ஹீமாட்டாலஜி சேவை , ஜோசப் கரேராஸ் லுகேமியா ஆராய்ச்சி நிறுவனம் , உயிர் மருத்துவ மரபியல் , அண்ணா பிக , மருத்துவமனை டெல் மார் மருத்துவ ஆராய்ச்சி நிறுவனம் ,

Researchers discover cells responsible for resistance to T-ALL treatment


Researchers discover cells responsible for resistance to T-ALL treatment
T-cell acute lymphoblastic leukemia (T-ALL) is a cancer of the blood that affects mainly children, but also less frequently adults. In adults, although the response to treatment might be initially positive, relapses are common and have a poor prognosis.
A collaborative project between IRB Barcelona s Biomedical Genomics lab, headed by ICREA researcher Núria López-Bigas, Anna Bigas group at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar), and Josep Maria Ribera s lab at the Josep Carreras Leukaemia Research Institute (IJC) has discovered that the cells responsible for resistance to T-ALL treatment in adults are already present in the tumors before diagnosis. ....

Comunidad Autonoma De Cataluna , Josep Mar , Triasi Pujol , Anna Bigas , Josep Maria Ribera , Emily Henderson , Research Group , Haematology Service , Josep Carreras Leukaemia Research Institute , Biomedical Genomics , Anna Biga , Hospital Del Mar Medical Research Institute , Hospital Del Mar , Santiago Gonz , Germans Trias , Pujol Hospital , Stem Cell , காமுனிடட தன்னாட்சி டி கடலுள் , ஜோசப் மார் , அண்ணா போகஸ் , ஜோசப் மரியா ரிபேரா , எமிலி ஹென்டர்சன் , ஆராய்ச்சி குழு , ஹீமாட்டாலஜி சேவை , ஜோசப் கரேராஸ் லுகேமியா ஆராய்ச்சி நிறுவனம் , உயிர் மருத்துவ மரபியல் ,