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MD Anderson Research Highlights for May 8, 2024

MD Anderson Research Highlights for May 8, 2024
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United States , Chris Brosey , Traver Hart , Jordi Rodon , Jonathan Kurie , Ann Klopp , American Association For Cancer Research , Nature Communications , Cancer Center , Research Highlights , American Association , Cancer Research , Annual Meeting , Funda Meric Bernstam , John Tainer , Nature Chemical , Chibawanye Ene , Hodgkin Lymphoma , Chijioke Nze ,

Lactate-producing bacteria inside tumors found to promote resistance to radiation therapy

Lactate-producing bacteria inside tumors found to promote resistance to radiation therapy
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United States , Lauren Colbert , Laurene Colbert , Ann Klopp , University Of Texas Md Anderson Cancer Center , Cancer Cell , Cancer Center , Radiation Oncology , Tumor Resident Lactobacillus ,

Lactate-producing bacteria inside tumors prom

<p>Researchers at <a href="https://www.mdanderson.org/">The University of Texas MD Anderson Cancer Center</a> have discovered that lactate-producing intratumoral bacteria drives resistance to <a href="https://www.mdanderson.org/treatment-options/radiation-therapy.html">radiation therapy</a>,&nbsp; suggesting that lactic acid-producing bacteria present in various cancers may serve as novel therapeutic targets. The study, published today in <a href="https://www.cell.com/cancer-cell/fulltext/S1535-6108(23)00328-8"><em>Cancer Cell</em></a>, reported that a particular bacterial species, <em>Lactobacillus iners </em><em>(L. iners)</em>, caused cancer cells to respond to radiation by rewiring metabolic signaling pathways to resist treatment. The researchers also found that <em>L. iners</em> was associated with poorer clinical outcomes in patients with <a href="ht ....

United States , Ann Klopp , Lauren Colbert , Radiological Society Of North America , University Of Texas Md Anderson Cancer Center , Research Institute Of Texas , National Institutes Of Health Cancer Institute , Cancer Center , Cancer Cell , Radiation Oncology , Related Cancers Moon , Radiological Society , North America , National Institutes , National Cancer Institute , Cancer Prevention , Research Institute ,