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RYBREVANT™ (amivantamab-vmjw) Receives FDA Approval as the First Targeted Treatment for Patients with Non-Small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations


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HORSHAM, Pa., May 21, 2021 /PRNewswire/  The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the U.S. Food and Drug Administration (FDA) has granted the accelerated approval of RYBREVANT
TM (amivantamab-vmjw) for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, as detected by an FDA-approved test, whose disease has progressed on or after platinum-based chemotherapy.
1 RYBREVANT
TM is the first fully-human, bispecific antibody approved for the treatment of patients with NSCLC that targets EGFR exon 20 insertion mutations, which are the third most prevalent activating EGFR mutation. ....

United States , Jill Feldman , Christopher Delorefice , Joshuak Sabari , Peter Lebowitz , Janssen Carepath , Rybrevant Janssencarepathsavings , Jennifer Mcintyre , Ania Diantonio , Mathai Mammen , National Cancer Institute , Janssen Biotech Inc , Janssen Pharmaceutical Companies Of Johnson , Janssen Research Development , Janssen Carepath Savings Program , York University Langone Perlmutter Cancer Center , American Cancer Society , None Of The Janssen Pharmaceutical Companies , Virtual Scientific Program , Drug Administration , Guardant Health , World Health Organization , Yuhan Corporation , Society Of Clinical Oncology , Exchange Commission , Companies Of Johnson ,