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New nasal spray delivers antipsychotic medication directly to the brain


New nasal spray delivers antipsychotic medication directly to the brain
A team of neuroscientists and engineers at McMaster University has created a nasal spray to deliver antipsychotic medication directly to the brain instead of having it pass through the body.
The leap in efficiency means patients with schizophrenia, bipolar disorder and other conditions could see their doses of powerful antipsychotic medications cut by as much as three quarters, which is expected to spare them from sometimes-debilitating side effects while also significantly reducing the frequency of required treatment.
The new method delivers medication in a spray that reaches the brain directly through the nose, offering patients greater ease of use and the promise of improved quality of life, including more reliable, effective treatment. ....

Rodney Johnson , Ram Mishra , Fahed Abuhijleh , Michael Majcher , Todd Hoare , Emily Henderson , Mcmaster University , Mcmaster University Interdisciplinary Research Fund , Engineering Research Council Of Canada , Natural Sciences , Department Of Psychiatry , Canadian Institutes Of Health Research , Collaborative Health Research Partnership Grant , Mcmaster School Of Biomedical Engineering , Canada Research , University Of Minnesota , Behavioural Neurosciences , Biomedical Engineering , Canada Research Chair , Chemical Engineering , Wali Babar , Andrew Lofts , Engineering Research Council , Canadian Institutes , Health Research , Interdisciplinary Research ,

New delivery method promises relief from antipsychotic medication's adverse side effects


Credit: Georgia Kirkos, Mcmaster University
HAMILTON, ON, Jan. 15, 2021 A team of neuroscientists and engineers at McMaster University has created a nasal spray to deliver antipsychotic medication directly to the brain instead of having it pass through the body.
The leap in efficiency means patients with schizophrenia, bipolar disorder and other conditions could see their doses of powerful antipsychotic medications cut by as much as three quarters, which is expected to spare them from sometimes-debilitating side effects while also significantly reducing the frequency of required treatment.
The new method delivers medication in a spray that reaches the brain directly through the nose, offering patients greater ease of use and the promise of improved quality of life, including more reliable, effective treatment. ....

Rodney Johnson , Ram Mishra , Fahed Abuhijleh , Michael Majcher , Todd Hoare , Mcmaster University , Mcmaster University Interdisciplinary Research Fund , Engineering Research Council Of Canada , Natural Sciences , Department Of Psychiatry , Canadian Institutes Of Health Research , Collaborative Health Research Partnership Grant , Mcmaster School Of Biomedical Engineering , Canada Research , University Of Minnesota , Behavioural Neurosciences , Biomedical Engineering , Canada Research Chair , Chemical Engineering , Wali Babar , Andrew Lofts , Engineering Research Council , Canadian Institutes , Health Research , Interdisciplinary Research , Biomedical Environmental Chemical Engineering ,