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Royal Papworth Hospital gains £3.4m funding for home monitoring trials

Royal Papworth Hospital gains £3.4m funding for home monitoring trials
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Researchers recognised by 2022 Academy of Medical Sciences Fellowships

Researchers recognised by 2022 Academy of Medical Sciences Fellowships
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Ability of multi-drug resistant infection to evolve within cystic fibrosis patients highlights need for rapid treatment

Ability of multi-drug resistant infection to evolve within cystic fibrosis patients highlights need for rapid treatment Scientists have been able to track how a multi-drug resistant organism is able to evolve and spread widely among cystic fibrosis patients – showing that it can evolve rapidly within an individual during chronic infection. We hope insights from our research will help us reduce the risk of transmission, stop the bug evolving further, and potentially prevent the emergence of new pathogenic variants Julian Parkhill Around one in 2,500 children in the UK is born with cystic fibrosis, a hereditary condition that causes the lungs to become clogged up with thick, sticky mucus. The condition tends to decrease life expectancy among patients.

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Multi-drug resistant infection about to evolve within cystic fibrosis patients

 E-Mail Scientists have been able to track how a multi-drug resistant organism is able to evolve and spread widely among cystic fibrosis patients - showing that it can evolve rapidly within an individual during chronic infection. The researchers say their findings highlight the need to treat patients with Mycobacterium abscessus infection immediately, counter to current medical practice. Around one in 2,500 children in the UK is born with cystic fibrosis, a hereditary condition that causes the lungs to become clogged up with thick, sticky mucus. The condition tends to decrease life expectancy among patients. In recent years, M. abscessus, a species of multi-drug resistant bacteria, has emerged as a significant global threat to individuals with cystic fibrosis and other lung diseases. It can cause a severe pneumonia leading to accelerated inflammatory damage to the lungs, and may prevent safe lung transplantation. It is also extremely difficult to treat - fewer than one in thr

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Ability of multi-drug resistant infection to evolve within cystic fibrosis patients highlights need for rapid treatment

Ability of multi-drug resistant infection to evolve within cystic fibrosis patients highlights need for rapid treatment
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