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Fungal involvement in tumors may drive worse cancer outcomes

The presence of some fungal species in tumors predicts-;and may even help drive-;worse cancer outcomes, according to a study from Weill Cornell Medicine and Duke University researchers. ....

Anders Dohlman , Iliyan Iliev , Emily Henderson , Steven Lipkin , Edward Meyer Cancer Center , Division Of Gastroenterology , Jill Roberts Institute For Research , Presbyterian Weill Cornell Medical Center , Duke University , Epigenetics Program , Weill Cornell Medicine , Jill Roberts Institute , Inflammatory Bowel Disease , Weill Cornell , Cancer Genome Atlas , Roland Harriman Professor , Joan Weill Department , Genomics Industry Focus , Cancer Genetics , Weill Cornell Medical ,

Fungal association with tumors may predict worse outcomes

Fungal association with tumors may predict worse outcomes
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Irmat Hirschl , Anders Dohlman , Iliyan Iliev , Steven Lipkin , Colitis Foundation , Burroughs Wellcome Fund , Division Of Gastroenterology , Harryb Helmsley Charitable , Presbyterian Weill Cornell Medical Center , Cancer Research Institute , Edward Meyer Cancer Center , Jill Roberts Institute For Research , Epigenetics Program , Us National Institutes Of Health , Duke University , Weill Cornell Medicine , Jill Roberts Institute , Inflammatory Bowel Disease , Weill Cornell , Cancer Genome Atlas , Roland Harriman Professor , Joan Weill Department , Cancer Genetics , Weill Cornell Medical , Charitable Trust , Career Scientist Award ,

Cells construct living composite polymers for biomedical applications

Biomedical engineers at Duke University have demonstrated that a class of interwoven composite materials called semi-interpenetrating polymer networks (sIPNs) can be produced by living cells. The approach could make these versatile materials more biologically compatible for biomedical applications such as time-delayed drug delivery systems. ....

Jinhui Tang , Lihua Wang , Xiaoyu Yang , Xiling Shen Lingchong , Pengcheng Li , Anders Dohlman , Zhuojun Dai , Feilun Wu , Kun Xiang , Nature Communications , National Natural Science Foundation Of China , National Institutes Of Health , Shenzhen Institute Of Synthetic Biology , Development Program Of China , Shenzhen Peacock Team Project , National Key Research , Us Army Research , Duke University , Lingchong You , Shenzhen Institute , Synthetic Biology , Development Program , National Institutes , Lucile Packard Fellowship , National Natural Science Foundation , Lei Dai ,

The Cancer Microbiome Atlas gives clearer picture of microbiota living in organs

The Cancer Microbiome Atlas gives clearer picture of microbiota living in organs
Biomedical engineers at Duke University have devised an algorithm to remove contaminated microbial genetic information from The Cancer Genome Atlas (TCGA). With a clearer picture of the microbiota living in various organs in both healthy and cancerous states, researchers will now be able to find new biomarkers of disease and better understand how numerous cancers affect the human body.
In the first study using the newly decontaminated dataset, the researchers have already discovered that normal and cancerous organ tissues have a slightly different microbiota composition, that bacteria from these diseased sites can enter the bloodstream, and that this bacterial information could help diagnose cancer and predict patient outcomes. ....

Xiling Shen , Anders Dohlman , Microbiome Atlas , Emily Henderson , Duke University , Cancer Genome Atlas , Cell Host , Hawkins Family Associate Professor , Biomedical Engineering , Cancer Microbiome Atlas , Colorectal Cancer , Genetic Information , எமிலி ஹென்டர்சன் , டியூக் பல்கலைக்கழகம் , புற்றுநோய் மரபணு அட்லஸ் , செல் தொகுப்பாளர் , ஹாக்கின்ஸ் குடும்பம் இணை ப்ரொஃபெஸர் , உயிர் மருத்துவ பொறியியல் , பெருங்குடல் புற்றுநோய் , ஜெநெடிக் தகவல் ,

Duke researchers boost cancer fight by targeting bacterial biomarker data

by Ken Kingery January 14, 2021 .
DURHAM – Biomedical engineers at Duke University have devised an algorithm to remove contaminated microbial genetic information from The Cancer Genome Atlas (TCGA). With a clearer picture of the microbiota living in various organs in both healthy and cancerous states, researchers will now be able to find new biomarkers of disease and better understand how numerous cancers affect the human body.
In the first study using the newly decontaminated dataset, the researchers have already discovered that normal and cancerous organ tissues have a slightly different microbiota composition, that bacteria from these diseased sites can enter the bloodstream, and that this bacterial information could help diagnose cancer and predict patient outcomes. ....

Xiling Shen , Anders Dohlman , Microbiome Atlas , National Institutes Of Health , Defense Advanced Research Projects Agency , Duke University , Cell Host , Hawkins Family Associate Professor , Biomedical Engineering , Cancer Microbiome Atlas , National Institutes , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , டியூக் பல்கலைக்கழகம் , செல் தொகுப்பாளர் , ஹாக்கின்ஸ் குடும்பம் இணை ப்ரொஃபெஸர் , உயிர் மருத்துவ பொறியியல் , தேசிய நிறுவனங்கள் ,