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Clene Reports Reduction in Biomarker Plasma Neurofilament Light (NfL) Levels and Improved Survival With CNM-Au8® Treatment From HEALEY ALS Platform Trial Long-Term Open Label Extension

Clene Reports Reduction in Biomarker Plasma Neurofilament Light (NfL) Levels and Improved Survival With CNM-Au8® Treatment From HEALEY ALS Platform Trial Long-Term Open Label Extension
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Salt lake cityUnited statesJamesd berrySeanm healeyIgnacio guerrero rosBenjamin greenbergClene nanomedicine incAnalysis validates association of nfMotor neuron disorder divisionCleneclene incNeurological clinical research institute at massachusettsClene incNeurology departmentSecurities exchangeDavid schullrusso partnersTerm plasma nfl biomarker findings

Clene Reports Reduction in Biomarker Plasma Neurofilament Light (NfL) Levels and Improved

CNM-Au8 30mg treatment demonstrated significantly reduced plasma neurofilament light chain (NfL) levels at 76 weeks relative to placebo (18 months from randomization, p=0.023)60% decreased risk of long-term all-cause mortality (>18

Salt lake cityUnited statesBenjamin greenbergJamesd berrySeanm healeyMotor neuron disorder divisionNeurology departmentSecurities exchangeClene incClene nanomedicine incNeurological clinical research institute at massachusettsAnalysis validates association of nfTerm plasma nfl biomarker findingsTrial open label extensionMixed modelRepeat measures