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Cholesterol starvation kills lymphoma cells


Drug is being developed for clinical trials
Drug selectively attacks cancer cells, leaves normal cells unharmed
CHICAGO - Scientists at Northwestern Medicine have developed a novel therapy to trick cancer cells into gobbling up what they think is their favorite food - cholesterol - which actually triggers their destruction. What appears to them as a cholesterol-loaded particle is actually a synthetic nanoparticle that binds to the cancer cells and starves them to death.
Although the research looked at lymphoma cells, scientists say the new experimental drug from Northwestern could be effective in other cancers with a similar appetite for cholesterol, such as kidney and ovarian cancer. ....

Northwestern University , United States , Tim Taxter , Amir Behdad , Jonathan Moreira , Shuo Yang , Adam Yuh Lin , Kaylinm Mcmahon , Reem Karmali , Andreae Calvert , Leoi Gordon , National Cancer Institute , National Institutes Of Health , Roberth Lurie Comprehensive Cancer Center , National Heart , Blood Institute , Northwestern Medicine , Biological Chemistry , John Friend Professor , Cancer Research , Northwestern University Feinberg School , Comprehensive Cancer Center , National Institutes , Comprehensive Cancer Center Support , வடமேற்கு பல்கலைக்கழகம் , ஒன்றுபட்டது மாநிலங்களில் ,