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Early last year, Angela Reiersen, a psychiatrist at Washington University in St. Louis, took ill with what she suspected was COVID-19. Because of a shortage of tests at the time, she never found out for sure, and she recovered before long. But the experience got her thinking about something. Reiersen had recently seen research suggesting that an antidepressant called fluvoxamine was useful in treating sepsis, a potentially fatal condition in which the body releases a dangerous imbalance of chemicals known as cytokines into the bloodstream in response to an infection. Might fluvoxamine also be effective in treating COVID-19? On March 25, Reiersen sent an email to a colleague, Eric Lenze, also a psychiatrist, asking what he thought of her idea. Lenze was equally intrigued.

United statesGolden gate fieldsFrance generalLos angelesEric lenzeNicolas hoertelDavid seftelAngela reiersenLeigh turnerSteve kirschRobert silicianoJohns hopkins universityWashington university schoolLos angeles timesDrug administrationParis university