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Synergistic Treatment of Malignant Tumors

Reporting a ‘Dandelion’ like sequential drug delivery system to realize the sequential release of different drugs for treating malignant tumors. ....

Nordrhein Westfalen , United States , United Kingdom , Malvern Zetasizer Nano , Beyotime Institute Of Biotechnology Shanghai , Laboratory Animals , Graphpad Software Inc , Committee In Yanshan University , Malvern Instrument Co Ltd , River Laboratory Animal Technology Co Ltd , Shimadzu Co Ltd , Photothermal Properties , Alladin Reagent Company Shanghai , Hongshun Biological Technology Co Ltd , Sangon Biotech , Alladin Reagent Company , Cytotoxicity Assay Kits , Yaji Biotech , Modified Eagle Medium , Thermo Science , Reactive Oxygen Species Assay Kits , Assay Kit , Beyotime Institute , American Type Cell Culture , National Institutes , Health Guide ,

[Full text] Bioactive Compounds from Germinated Brown Rice Protect Cardiomyocytes

Discussion
There are several therapeutic approaches to bio-functional foods against cardiovascular diseases, both in experimental and clinical studies. Germinated Brown Rice (GBR) exerted its protective properties on cardiovascular diseases and related-cardiovascular metabolism dysfunction, including hypertension, hyperlipidemia, and diabetes. Here, this is the first study to represent the cardioprotective effect of GBR on cardiomyocyte-simulated I/R injury. The significant findings in this study indicated that simulation of I/R promoted the percentage of cell death and total cell apoptosis. Additionally, ischemic/reperfusion induction disrupted the mitochondria membrane potential and mitochondria respiration. On the other hand, pretreatment with GBR could significantly reverse all impacts of simulated I/R injury. Therefore, GBR can offer cardioprotection on I/R injury. ....

United States , Sakon Nakhon , Annexinv Propidium , Life Technologies Inc , Life Technologies , Mito Stress Test , Seahorse Bioscience , Bioactive Compound , American Type Cell Culture , Modified Eagle , Cell Death , Cell Apoptosis , Propidium Iodine , Mitochondria Membrane Potential Alteration , Extracellular Flux , Graphpad Prism , Protective Property , Junn Terminal , ஒன்றுபட்டது மாநிலங்களில் , சாகோன் னக்கோன் , வாழ்க்கை தொழில்நுட்பங்கள் இன்க் , வாழ்க்கை தொழில்நுட்பங்கள் , மீதோ மன அழுத்தம் சோதனை , கடற்குதிரை உயிர் அறிவியல் , அமெரிக்கன் வகை செல் கலாச்சாரம் , மாற்றப்பட்டது கழுகு ,