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Combining biochemical and topographical cues improves quality of skeletal muscle regeneration


Combining biochemical and topographical cues improves quality of skeletal muscle regeneration
When trauma, illness, or injury causes significant muscle loss, reconstructive procedures for bioengineering functional skeletal muscles can fall short, resulting in permanent impairments.
Finding a synergy in the importance of biochemical signals and topographical cues, researchers from Wake Forest Institute for Regenerative Medicine, Sungkyunkwan University, and Chonnam National University developed an efficient technique for muscle regeneration and functional restoration in injured rats. They describe results from the technique in the journal Applied Physics Reviews, from AIP Publishing.
The group expanded on a method they previously developed using muscle-specific materials derived from an organism s tissues (dECM-MA) to construct bioinks, which are materials used for 3D-printing tissue. ....

Jin Lee , Emily Henderson , Sungkyunkwan University , Wake Forest Institute For Regenerative Medicine , Chonnam National University , Wake Forest Institute , Regenerative Medicine , Applied Physics Reviews , Study Author , American Instiitute , ஜின் லீ , எமிலி ஹென்டர்சன் , எழுந்திரு காடு நிறுவனம் க்கு மீளுருவாக்கம் மருந்து , எழுந்திரு காடு நிறுவனம் , மீளுருவாக்கம் மருந்து , பயன்படுத்தப்பட்டது இயற்பியல் மதிப்புரைகள் , படிப்பு நூலாசிரியர் ,