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Vivoryon Therapeutics N.V.: Vivoryon Therapeutics to Host Virtual Event on Current Clinical Landscape in Alzheimer's Disease Treatment Options with Leaders and Experts on April 15th, 2021


01.04.2021 - 07:02 Uhr
Vivoryon Therapeutics N.V.: Vivoryon Therapeutics to Host Virtual Event on Current Clinical Landscape in Alzheimer s Disease Treatment Options with Leaders and Experts on April 15th, 2021
Vivoryon Therapeutics N.V., NL00150002Q7Despite repeated clinical trial failures in the AD space, a determined group of pharma and biotech companies has not given up on seeking for therapies that address the high unmet medical need in this indication. Vivoryon s interactive session will cover discussions surrounding current hurdles and exciting, novel approaches to the challenging AD space, including the company s clinical phase 2 compound, varoglutamstat, a small molecule inhibitor of glutaminyl cyclase (QC) capable of targeting all three hallmarks of AD: amyloid-beta, tau, and neuroinflammation. ....

Noord Holland , Ulrich Dauer , Halle Saale , Philip Scheltens , Howard Feldman , Frank Weber , Dementia Fund , English Company , Alzheimer Center Amsterdam , Department Of Neurosciences , Distribution Services , Alzheimer Disease Cooperative Study , Us National Institutes On , News Service , Communications Gretchen Schweitzer Valeria Fisher Tel , Disease Puzzle , Professor Philip Scheltens , Managing Partner , Disease Cooperative Study , California San Diego School , Chief Medical Officer , European Alzheimer , Disease Phase , Communications Gretchen Schweitzer , Valeria Fisher Tel , Forward Looking Statementsinformation ,

Vivoryon Therapeutics N.V.: Vivoryon Therapeutics to Host Virtual Event on Current Clinical Landscap


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01-Apr-2021
Vivoryon Therapeutics N.V.: Vivoryon Therapeutics to Host Virtual Event on Current Clinical Landscape in Alzheimer s Disease Treatment Options with Leaders and Experts on April 15th, 2021
DGAP-News: Vivoryon Therapeutics N.V.
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01.04.2021 / 07:00
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Vivoryon Therapeutics to Host Virtual Event on Current Clinical Landscape in Alzheimer s Disease Treatment Options with Leaders and Experts on April 15
th, 2021
HALLE (SAALE) / MUNICH, GERMANY, 1 April 2021 - Vivoryon Therapeutics N.V. (Euronext Amsterdam: VVY; NL00150002Q7) (
Vivoryon) announced today that it will host a virtual event covering next steps in Alzheimer s Disease (AD) treatment options with leaders and experts in the field on Thursday, April 15 ....

Ulrich Dauer , Gretchen Schweitzer Valeria Fisher , Philip Scheltens , Howard Feldman , Frank Weber , Dementia Fund , Alzheimer Disease Cooperative Study , Us National Institutes On , Alzheimer Center Amsterdam , Trophic Communications , Department Of Neurosciences , Distribution Services , Host Virtual Event , Current Clinical Landscape , Disease Treatment Options , Euronext Amsterdam , Disease Puzzle , Managing Partner , Disease Cooperative Study , California San Diego School , Chief Medical Officer , European Alzheimer , Disease Phase , Corporate News , Regulatory Announcements , உல்ரிச் அச்சுறுத்தல் ,

AB Science announces that a new independent publication confirms the role of masitinib as a potential therapy in neurodegenerative disorders including Alzheimer's Disease


in vitro and
in vivo (APPswe/PS1dE9 mouse model of Alzheimer’s disease) experiments that show increased mast cell hemichannel activity after treatment with amyloid peptide (Ab
25–35), with subsequent degranulation response and enhanced histamine release [2]. The number of mast cells in hippocampal and cortical areas increased drastically even before amyloid plaque deposits became evident, suggesting that mast cells are one of the first brain cells to recognize and respond to amyloid peptides, and thus may play a critical role in the onset and progression of Alzheimer’s disease. Treatment with masitinib was shown to totally prevent the amyloid-induced hemichannel-dependent mast cell activity in bone marrow-derived mast cells and brain mast cells. The authors concluded that hemichannel expressed by mast cells might serve as a molecular target with which to develop therapeutic treatments that could delay the onset and progression of Alzheimer’s disease. ....

United States , France General , Arthur Rouill , Jeffrey Freedman , Philip Scheltens , International Journal Of Molecular Sciences , Alzheimer Center Amsterdam , Mast Cell , Astrocyte Hemichannels , Their Role , Harmful Stress Conditions , International Journal , Molecular Sciences , Disease Assessment Scale Cognitive Subscale , Disease Cooperative Study Activities , Daily Living , Care Required , Peptide Induced Degranulation , Are Activated , Brain Mast Cells , Euronext Paris , Des March , Ab Science Stock Exchange , Press Release , Ab Fr0010557264 , ஒன்றுபட்டது மாநிலங்களில் ,